Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01KOI
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| Former ID |
DNC003144
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| Drug Name |
4-(2-amino-1,3-thiazol-4-yl)phenol
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| Synonyms |
4-(2-Amino-1,3-thiazol-4-yl)phenol; 57634-55-6; 4-(2-amino-4-thiazolyl)phenol; 4-(2-Amino-thiazol-4-yl)-phenol; 4-(2-aminothiazol-4-yl)phenol; CHEMBL483790; QGSJYYIRAFRPIT-UHFFFAOYSA-N; Phenol, 4-(2-amino-4-thiazolyl)-; 2-amino-4-(4-hydroxyphenyl)-thiazole; NSC405294; 3fu3; Oprea1_415030; SCHEMBL5321407; p-(2-Amino-4-thiazolyl)phenol; CTK5A7198; DTXSID30323956; MolPort-000-141-769; HMS3604B06; Phenol,4-(2-amino-4-thiazolyl)-; AC1L8637; KS-00000A4L; ZINC16951624; STK723345; SBB018017; BDBM50293592; KM0129; 5926AE; 4-(2-Aminothiazol-4-yl)phenol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H8N2OS
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| Canonical SMILES |
C1=CC(=CC=C1C2=CSC(=N2)N)O
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| InChI |
1S/C9H8N2OS/c10-9-11-8(5-13-9)6-1-3-7(12)4-2-6/h1-5,12H,(H2,10,11)
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| InChIKey |
QGSJYYIRAFRPIT-UHFFFAOYSA-N
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| CAS Number |
CAS 57634-55-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
475407, 3256672, 4108933, 4890305, 6671334, 7924177, 8904985, 11536848, 16435659, 16960196, 41493927, 48381334, 52667392, 60344608, 84981881, 87619588, 99443763, 103655055, 104135143, 104572149, 104850524, 117652718, 117823683, 118081184, 125417513, 129020553, 130024265, 131319487, 131396323, 131499518, 134351285, 135599286, 139433810, 140007255, 143406297, 144024673, 160968375, 162140242, 162875515, 163587279, 164767603, 164868738, 170302069, 170482133, 179065193, 184593940, 186003545, 187560429, 202565695, 223250184
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fructose-1,6-bisphosphatase (FBP) | Target Info | Inhibitor | [2] |
| Leukotriene A-4 hydrolase (LTA4H) | Target Info | Inhibitor | [1] | |
| BioCyc | Leukotriene biosynthesis | |||
| Gluconeogenesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Glycolysis / Gluconeogenesis | ||||
| Pentose phosphate pathway | ||||
| Fructose and mannose metabolism | ||||
| Biosynthesis of antibiotics | ||||
| Carbon metabolism | ||||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Glucagon signaling pathway | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Fructose and Mannose Degradation | ||||
| Pentose Phosphate Pathway | ||||
| Gluconeogenesis | ||||
| Reactome | Gluconeogenesis | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| Glycolysis and Gluconeogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
| REF 2 | A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase. Bioorg Med Chem. 2009 Jun 1;17(11):3916-22. | |||
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