Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00UDX
|
|||
| Former ID |
DNC003301
|
|||
| Drug Name |
1-Guanidinium-7-Aminoheptane
|
|||
| Synonyms |
1-Guanidinium-7-aminoheptane; 1-GUANIDINIUM-7-AMINOHEPTANE; AC1NRBDQ; N-(7-aminoheptyl)methanetriamine; N"-(7-aminoheptyl)methanetriamine; GC7
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C8H22N4
|
|||
| Canonical SMILES |
C(CCCN)CCCNC(N)N
|
|||
| InChI |
1S/C8H22N4/c9-6-4-2-1-3-5-7-12-8(10)11/h8,12H,1-7,9-11H2
|
|||
| InChIKey |
SKGAVCHIFDRDTK-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Deoxyhypusine synthase (DHPS) | Target Info | Inhibitor | [1], [2] |
| BioCyc | Hypusine biosynthesis | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| WikiPathways | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
| REF 2 | Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture. Biochim Biophys Acta. 1996 Jan 10;1310(1):119-26. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.