Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00ENY
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| Former ID |
DAP000015
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| Drug Name |
L-Glutamic Acid
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| Synonyms |
Aciglut; Glu; Glusate; Glut; Glutacid; Glutamicol; Glutamidex; Glutaminol; Glutaton; Gulutamine; Acide glutamique; Acido glutamico; Acidum glutamicum; Acidum glutaminicum; Glutamic acid polymer; Glutaminic acid; E 620; A-Aminoglutaric acid; A-Glutamic acid; Acide glutamique [INN-French]; Acido glutamico [INN-Spanish]; Acidum glutamicum [INN-Latin]; D-Glutamiensuur; Glutamic Acid [USAN:INN]; Glutamic acid (VAN); Glutaminic acid (VAN); Gulutamine (USP); L-Glutamic acid hydrochloride; L-Glutaminic acid; L-Glutaminsaeure; L-glu; L-glutamate; Alpha-Aminoglutaric acid (VAN); Alpha-L-Glutamic acid polymer; Glutamic Acid (L-glutamic acid); Glutamic acid (H-3); H-Glu-OH; L-2-Aminoglutaric acid; L-Glutamic acid (9CI); L-Glutamic acid (JAN); L-Glutamic acid, homopolymer; L-a-Aminoglutaric acid; L-alpha-Aminoglutaric acid; Poly-L-glutamate; Sodium Glutamate (L-glutamic Acid); Glutamic acid, L-, peptides; L-Glutamic acid, homopolymer (9CI); Poly(alpha-L-glutamic acid); Glutamic acid, L-(7CI,8CI); L-(+)-glutamic acid; (S)-(+)-Glutamic acid; (S)-2-Aminopentanedioic acid; (S)-Glutamic acid; 1-Aminopropane-1,3-dicarboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD-11: 6A20; ICD-9: 295] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Dietary supplement
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| Structure |
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Download2D MOL |
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| Formula |
C5H9NO4
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| Canonical SMILES |
C(CC(=O)O)C(C(=O)O)N
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| InChI |
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
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| InChIKey |
WHUUTDBJXJRKMK-VKHMYHEASA-N
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| CAS Number |
CAS 56-86-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3327, 627126, 820094, 820617, 822192, 822517, 822724, 822932, 823119, 825074, 826975, 828108, 841758, 854467, 854468, 854502, 7847075, 7887923, 7979423, 8023666, 8026291, 8026293, 8143737, 8172949, 10527679, 11110117, 11110137, 11113412, 11528393, 11538992, 14710662, 14716143, 14719817, 14719819, 15297417, 16918839, 17404216, 17422134, 17422293, 24846358, 24872908, 24895052, 24895223, 24895340, 24901609, 24902257, 26746616, 26751652, 34674977, 46391925
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| ChEBI ID |
CHEBI:16015
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| SuperDrug ATC ID |
B03BB01
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| SuperDrug CAS ID |
cas=000059303
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Antagonist | [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1369). | |||
| REF 2 | Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia pati... Am J Psychiatry. 2008 Dec;165(12):1594-603. | |||
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