Resistance mutation info of drug
| Drug General Information | |||||||||||
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| Drug ID | D01RFF | ||||||||||
| Drug Name | Etoxazole | ||||||||||
| Synonyms | Etoxazole; 153233-91-1; 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole; Baroque; Borneo; TetraSan; Etoxazole [ISO]; 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole; HSDB 7277; 2-(2,6-Difluorophenyl)-4-(4-(1,1-dimethylethyl)-2-ethoxyphenyl)-4,5-dihydrooxazole; YI 5301; EINECS Annex I Index 603-199-00-8; CHEBI:39329; 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole; Oxazole, 2-(2,6-difluorophenyl)-4-(4-(1,1-dimethylethyl)-2-ethoxyphenyl)-4 | ||||||||||
| Drug Type | Small molecular drug | ||||||||||
| Structure |
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| Drug Resistance Mutations | |||||||||||
| Target Name | Tetranychus urticae Chitin synthase 1 (chs1) | Target Info | |||||||||
| Gene Name | chs1 | ||||||||||
| Uniprot ID | H9U0G2_TETUR | ||||||||||
| Species | Tetranychus urticae | ||||||||||
| Reference Sequence |
MARETVKKWDVFVESPPPDDDETSSSEWIDVILKILKLCAYVITFIVVLACSVLSKGLVL FMTSIIKPNRTGLIICSHGIPSLDRDKKYEVVLNLSDPERVAWIWALIGVLIVPELMTLF RAARICTFKSIRRPSKAVFSLIFIVETLHTIGIVMLVFLILPSLDVTKGVILTNCFCFIP GCLSLFSRHSGEAGRGYKTLLDLLSVGAQLSGLILWSVAESTDNPVAIYIPITSLLISIG WWENYIDKKSPFRAIQRLAQIKEGLQKSRYFIYIFISAWKIILIFIATIILRLLVDGSAL YLFTQFKSAFTSHKILIIRDRSDLSKSLSDSNVGIESEWLEMPASTSAPIWMLILQISAS WFCYVFGKFACKICIQRISFASPLILSVPVTAMTLAQFCVLNFENSCSLNRFLPRYLFWS CPSADTFFTDGVFYNLHGIIWVIMYISQFWITFHIFNPKCERLATTEKLFVNPMYCGLLI DASMILNRRRDDKEVIKAGDIDKSVRDPDNVQDPSLHYETISEHPDDKKSTVQSTDFITK ILVCATMWHETSEEMIQMLKSVFRMDFDQSARHKAQKYLRVVDPDYYEFEVHILFDDAFE LSDDNDDYQVVNRFVKQFIEVIDTAASNIHQCEIRLKSPAKYPTPYGGKLEYVLPGGNKL HVHLKDKMKIRHRKRWSQVMYMYYLLGHRLMELPIDVNRKATMAENTYILTLDGDINFRP EAVQLLVDLMKKNKNLGAACGRIHPVGSGLMAWYQKFEYAVGHWLQKATEHMIGCVLCSP GCFSLFRAKALMDDNVMRKYTTRSDEALHYVQYDQGEDRWLCTLLLQRGYRVEYSAAADA YTHCPEGFGEFYTQRRRWAPSTMANILDLLGDYKRTVAVNDHISLLYIVYQGMLMVGTIL GPGTIFLMLVGAMVAVFRISNWDSFLFNLIPILIFIVICFTCKNDIQILVAQIMSACYAL LMMAVFVGTAIQMAEDGVTSPSAVFFIALSGSFVVAALLHPQEFHCLYPCLLYFLSIPCM YLLLMIYSLVNLNVVTWGTREVQSKKTKAELEEEKKAVEEIKKGNLLSFLNLNPNAKEEE GSIEFSLANLFRCSFCTYPKPNDEKIHLLKIEQHLSEMTDKLGALEKYLDPLGGPRRKGS SIGRNARFSDNLSTVTENEEHEDMDSIGSESQTDDMSIKDNEEVAPRFDEDHPYWIEDED LRDGEIKQLAENEIAFWKELISKYLYPIDQNKDHQARVAVELKELRNRVVFSFFMLNALF VLVVLILQLNKDILHVDWPYGIRENITFIPETNEIRIDKEYLEMEPIGLVFVGFFGLILL IQLIGMLFHRFGTLSHMLASVNLFQSKRDDISGEDDLKRNAIDIARQLQKLQGFNDGESS EDNTYGIAARKTIQKLEMRGRQTIKTGTLDVAFREKFMAILEAQEEGTTTPVLGGKRNRE TITALIKRSKNILGYDDHVGMQTLGIKNEFVRNPARSTLDSKQRRPPNPYGTNGMVNQAF DGLSSDEELEPPEVPMSTYRGINRKNLNGNSSQQL [Tetranychus urticae] |
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| Drug Resistance Mutations |
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| References | |||||||||||
| REF 1 | Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae.Insect Biochem Mol Biol.2014 May;48:17-28. | ||||||||||
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