Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99524 | Target Info | |||
| Target Name | Trace amine-associated receptor-1 (TAAR1) | ||||
| Synonyms |
Trace amine receptor 1; TaR-1; TAAR1
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| Target Type | Successful Target | ||||
| Gene Name | TAAR1 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Norepinephrine transporter (NET) | Successful Target | ||||
| UniProt ID | SC6A2_HUMAN | |||||
| Gene Name | SLC6A2 | |||||
| Synonyms |
Solute carrier family 6 member 2; Sodium-dependent noradrenaline transporter; SLC6A2; NET1; NET; NAT1
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| Representative Drug(s) | Dextroamphetamine | Drug Info | EC50 = 7.1 nM | [1] | ||
| Co-Target Name | Dopamine transporter (DAT) | Successful Target | ||||
| UniProt ID | SC6A3_HUMAN | |||||
| Gene Name | SLC6A3 | |||||
| Synonyms |
Solute carrier family 6 member 3; Sodium-dependent dopamine transporter; DAT1; DAT; DA transporter
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| Representative Drug(s) | Dextroamphetamine | Drug Info | EC50 = 24.8 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. Bioorg Med Chem. 2011 Dec 1;19(23):7044-8. | ||||
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