Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T97035 | Target Info | |||
| Target Name | Tyrosinase (TYR) | ||||
| Synonyms |
Tumor rejection antigen AB; SK29-AB; Monophenol monooxygenase; LB24-AB
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| Target Type | Successful Target | ||||
| Gene Name | TYR | ||||
| Biochemical Class | Paired donor oxygen oxidoreductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Carbonic anhydrase II (CA-II) | Successful Target | ||||
| UniProt ID | CAH2_HUMAN | |||||
| Gene Name | CA2 | |||||
| Synonyms |
Carbonic anhydrase C; Carbonic anhydrase 2; Carbonate dehydratase II; CAC
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| Representative Drug(s) | Hydroquinone | Drug Info | Ki = 90 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid. Bioorg Med Chem. 2008 Aug 1;16(15):7424-8. | ||||
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