Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T95558 Target Info
Target Name Diacylglycerol O-acyltransferase 2 (DGAT2)
Synonyms
UNQ738/PRO1433; HMFN1045; Diglyceride acyltransferase 2
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Target Type Successful Target
Gene Name DGAT2
Biochemical Class Acyltransferase
UniProt ID
DGAT2_HUMAN
Co-Targets of This Target  Top
Co-Target Name Nicotinic acid receptor (HCAR2) Successful Target
UniProt ID HCAR2_HUMAN
Gene Name HCAR2
Synonyms
Niacin receptor 1; NIACR1; Hydroxycarboxylic acid receptor 2; HM74A; HCA2; GPR109A; G-protein coupled receptor HM74A; G-protein coupled receptor 109A
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Representative Drug(s) Vitamin B3 Drug Info EC50 = 8.71 nM [1]
References  Top
REF 1 Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5620-3.

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