Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T88887 | Target Info | |||
| Target Name | Staphylococcus Plastid RNA polymerase beta (Stap-coc rpoB) | ||||
| Synonyms |
Transcriptase beta chain; RpoB; RNAP beta subunit; RNA polymerase beta subunit; DNA-directed RNA polymerase beta chain
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| Target Type | Successful Target | ||||
| Gene Name | Stap-coc rpoB | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Liver organic anion transporter 1 (SLCO1B1) | Literature-reported Target | ||||
| UniProt ID | SO1B1_HUMAN | |||||
| Gene Name | SLCO1B1 | |||||
| Synonyms |
Solute carrier organic anion transporter family member 1B1; Solute carrier family 21 member 6; Sodium-independent organic anion-transporting polypeptide 2; SLC21A6; OATPC; OATP2; OATP-C; OATP-2; Liver-specific organic anion transporter 1; LST1; LST-1
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| Representative Drug(s) | Rifamycin | Drug Info | IC50 = 230 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab Dispos. 2005 Apr;33(4):537-46. | ||||
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