Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T86192 | Target Info | |||
| Target Name | Voltage-gated potassium channel Kv7 (KCNQ) | ||||
| Synonyms |
Voltage-gated potassium channel subunit Kv7; Potassium voltage-gated channel subfamily KQT; Kv7; KVLQT; KQT-like; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT; IKs producing slow voltage-gated potassium channel alpha subunit KvLQT
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| Target Type | Clinical trial Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | Voltage-gated ion channel | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Voltage-gated potassium channel Kv7.2/Kv7.3 (KCNQ2/KCNQ3) | Co-Target | ||||
| UniProt ID | KCNQ2_HUMAN; KCNQ3_HUMAN | |||||
| Gene Name | KCNQ2; KCNQ3 | |||||
| Synonyms |
KQT-like 2; KQT-like 3
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| Representative Drug(s) | Flupirtine | Drug Info | EC50 = 560 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Design and evaluation of pyrazolopyrimidines as KCNQ channel modulators. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126603. | ||||
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