Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T85616 Target Info
Target Name Thioredoxin (TXN)
Synonyms
Trx; TRX1; TRDX; Surface-associated sulphydryl protein; Surface associated sulphydryl protein; SASP; ATL-derived factor; ADF
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Target Type Clinical trial Target
Gene Name TXN
UniProt ID
THIO_HUMAN
Co-Targets of This Target  Top
Co-Target Name COVID-19 non-structural protein 14 (nsp14) Literature-reported Target
UniProt ID R1AB_SARS2
Gene Name COVID-19 rep
Synonyms
COVID-19 Proofreading exoribonuclease; COVID-19 ExoN; COVID-19 Guanine-N7 methyltransferase
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Representative Drug(s) PX-12 Drug Info IC50 = 140 nM [1]
References  Top
REF 1 Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen.

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