Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T80942 | Target Info | |||
| Target Name | Matrix metalloproteinase (MMP) | ||||
| Synonyms |
Matrix metalloproteinase
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Angiotensin-converting enzyme (ACE) | Successful Target | ||||
| UniProt ID | ACE_HUMAN | |||||
| Gene Name | SLC33A1 | |||||
| Synonyms |
Kininase II; Dipeptidyl carboxypeptidase I; DCP1; DCP; CD143 antigen; CD143; ACE
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| Representative Drug(s) | S-3304 | Drug Info | IC50 ~ 1000 nM | [1] | ||
| Co-Target Name | Endothelin-converting enzyme 1 (ECE1) | Literature-reported Target | ||||
| UniProt ID | ECE1_HUMAN | |||||
| Gene Name | ECE1 | |||||
| Synonyms |
ECE-1
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| Representative Drug(s) | S-3304 | Drug Info | IC50 ~ 1000 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9. | ||||
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