Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T76904 Target Info
Target Name Catechol-O-methyl-transferase (COMT)
Synonyms
S-COMT; MB-COMT; Catechol-O-methyltransferase; COMT
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Target Type Successful Target
Gene Name COMT
Biochemical Class Methyltransferase
UniProt ID
COMT_HUMAN
Co-Targets of This Target  Top
Co-Target Name Dengue virus NS2B/NS3 protease (DENV NS2B/NS3) Literature-reported Target
UniProt ID POLG_DEN26
Gene Name DENV NS2B/NS3
Synonyms
Genome polyprotein
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Representative Drug(s) Tolcapone Drug Info IC50 = 640 nM [1]
References  Top
REF 1 Recent update on anti-dengue drug discovery. Eur J Med Chem. 2019 Aug 15;176:431-455.

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