Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T73482 Target Info
Target Name Orexin receptor type 1 (HCRTR1)
Synonyms
Ox1r; Ox1-R; Ox-1-R; Orexin-1 receptor; Hypocretin receptor type 1; HFGAN72 receptor; 7-transmembrane G-protein coupledneuropeptide receptor
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Target Type Clinical trial Target
Gene Name HCRTR1
Biochemical Class GPCR rhodopsin
UniProt ID
OX1R_HUMAN
Co-Targets of This Target  Top
Co-Target Name Orexin receptor type 2 (HCRTR2) Successful Target
UniProt ID OX2R_HUMAN
Gene Name HCRTR2
Synonyms
Ox2r; Ox2-R; Ox-2-R; Orexin-2 receptor; Hypocretin receptor type 2; HFGANP
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Representative Drug(s) SB-649868 Drug Info Ki = 0.3981 nM [1]
References  Top
REF 1 2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: a new class of selective orexin 2 antagonists. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6405-7.

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