Co-Target(s) Information
Target General Information | Top | ||||
---|---|---|---|---|---|
Target ID | T69991 | Target Info | |||
Target Name | Wee1-like protein kinase (WEE1) | ||||
Synonyms |
Wee1A kinase; WEE1hu
Click to Show/Hide
|
||||
Target Type | Clinical trial Target | ||||
Gene Name | WEE1 | ||||
Biochemical Class | Kinase | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
---|---|---|---|---|---|---|
Co-Target Name | Polo-like kinase 1 (PLK1) | Clinical trial Target | ||||
UniProt ID | PLK1_HUMAN | |||||
Gene Name | PLK1 | |||||
Synonyms |
Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase 13; Serine-threonine protein kinase 13; STPK13; Plk1; PLK-1; PLK; Mitoticserine-threonine kinase polo-like kinase 1
Click to Show/Hide
|
|||||
Representative Drug(s) | MK-1775 | Drug Info | IC50 = 350 nM | [1] | ||
Co-Target Name | Membrane-associated kinase (PKMYT1) | Literature-reported Target | ||||
UniProt ID | PMYT1_HUMAN | |||||
Gene Name | PKMYT1 | |||||
Synonyms |
Myt1 kinase; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; MYT1
Click to Show/Hide
|
|||||
Representative Drug(s) | MK-1775 | Drug Info | Ki = 470 nM | [2] |
References | Top | ||||
---|---|---|---|---|---|
REF 1 | Discovery of Inhibitors of Aurora/PLK Targets as Anticancer Agents. J Med Chem. 2019 Sep 12;62(17):7697-7707. | ||||
REF 2 | Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II. Bioorg Med Chem. 2018 Aug 7;26(14):4014-4024. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.