Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T69485 | Target Info | |||
| Target Name | Orexin receptor type 2 (HCRTR2) | ||||
| Synonyms |
Ox2r; Ox2-R; Ox-2-R; Orexin-2 receptor; Hypocretin receptor type 2; HFGANP
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| Target Type | Successful Target | ||||
| Gene Name | HCRTR2 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Orexin receptor type 1 (HCRTR1) | Clinical trial Target | ||||
| UniProt ID | OX1R_HUMAN | |||||
| Gene Name | HCRTR1 | |||||
| Synonyms |
Ox1r; Ox1-R; Ox-1-R; Orexin-1 receptor; Hypocretin receptor type 1; HFGAN72 receptor; 7-transmembrane G-protein coupledneuropeptide receptor
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| Representative Drug(s) | Suvorexant | Drug Info | Ki = 0.3981 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis. J Med Chem. 2020 Feb 27;63(4):1528-1543. | ||||
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