Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T62306 | Target Info | |||
| Target Name | Motilin receptor (MLNR) | ||||
| Synonyms |
MLNR; Gprotein coupled receptor 38
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| Target Type | Clinical trial Target | ||||
| Gene Name | MLNR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Growth hormone secretagogue receptor 1 (GHSR) | Successful Target | ||||
| UniProt ID | GHSR_HUMAN | |||||
| Gene Name | GHSR | |||||
| Synonyms |
Growth hormone secretagogue receptor; Ghrelin receptor; GHSR; GHS-R; GHRP; GH-releasing peptide receptor
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| Representative Drug(s) | Camicinal | Drug Info | EC50 ~ 1000 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate. J Med Chem. 2009 Feb 26;52(4):1180-9. | ||||
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