Co-Target(s) Information

Content Navigation (  All   None )                                      
Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T62187 Target Info
Target Name Herpes simplex virus Helicase-primase (HSV UL8)
Synonyms
Primase-associated factor; HEPA; DNA helicase/primase complex-associated protein
    Click to Show/Hide
Target Type Clinical trial Target
Gene Name HSV UL8
Biochemical Class Acid anhydrides hydrolase
UniProt ID
HEPA_HHV11
Co-Targets of This Target  Top
Co-Target Name Carbonic anhydrase II (CA-II) Successful Target
UniProt ID CAH2_HUMAN
Gene Name CA2
Synonyms
Carbonic anhydrase C; Carbonic anhydrase 2; Carbonate dehydratase II; CAC
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 12.8 nM [1]
Co-Target Name Carbonic anhydrase XII (CA-XII) Successful Target
UniProt ID CAH12_HUMAN
Gene Name CA12
Synonyms
Tumor antigen HOM-RCC-3.1.3; Carbonic anhydrase 12; Carbonate dehydratase XII
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 77.2 nM [1]
Co-Target Name Carbonic anhydrase I (CA-I) Successful Target
UniProt ID CAH1_HUMAN
Gene Name CA1
Synonyms
Carbonic anhydrase B; Carbonic anhydrase 1; Carbonate dehydratase I; CAB
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 323 nM [1]
Co-Target Name Carbonic anhydrase IX (CA-IX) Clinical trial Target
UniProt ID CAH9_HUMAN
Gene Name CA9
Synonyms
Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; PMW1; P54/58N; Membrane antigen MN; MN; G250 antigen (MN/CA IX/G250); G250; Carbonic anhydrase 9; Carbonate dehydratase IX; CAIX
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 81 nM [1]
Co-Target Name Carbonic anhydrase VB (CA5B) Co-Target
UniProt ID CAH5B_HUMAN
Gene Name CA5B
Synonyms
Carbonic anhydrase 5B, mitochondrial; Carbonate dehydratase VB; Carbonic anhydrase VB; CA-VB
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 389 nM [1]
Co-Target Name Carbonic anhydrase VA (CA5A) Co-Target
UniProt ID CAH5A_HUMAN
Gene Name CA5A
Synonyms
Carbonic anhydrase 5A, mitochondrial; Carbonate dehydratase VA; CA-VA
    Click to Show/Hide
Representative Drug(s) BAY 57-1293 Drug Info Ki = 474 nM [1]
References  Top
REF 1 Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. J Med Chem. 2017 Apr 13;60(7):3154-64.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.