Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T56518 | Target Info | |||
| Target Name | Hepatitis B virus Reverse transcriptase (HBV RT) | ||||
| Synonyms |
P; HBV reverse transcriptase
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| Target Type | Successful Target | ||||
| Gene Name | HBV RT | ||||
| Biochemical Class | DNA-directed DNA polymerase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Hepatitis B virus Capsid protein (HBV C) | Co-Target | ||||
| UniProt ID | CAPSD_HBVA3 | |||||
| Gene Name | HBV C | |||||
| Synonyms |
Hepatitis B virus Core antigen; Hepatitis B virus Core protein; Hepatitis B virus HBcAg; Hepatitis B virus p21.5
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| Representative Drug(s) | Entecavir | Drug Info | EC50 = 0.24 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4). Bioorg Med Chem. 2017 Feb 1;25(3):1042-1056. | ||||
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