Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T54771 Target Info
Target Name Sodium/glucose cotransporter 1 (SGLT1)
Synonyms
Solute carrier family 5 member 1; Na(+)/glucose cotransporter 1; NAGT; High affinity sodium-glucose cotransporter
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Target Type Clinical trial Target
Gene Name SLC5A1
Biochemical Class Solute:sodium symporter
UniProt ID
SC5A1_HUMAN
Co-Targets of This Target  Top
Co-Target Name Sodium/glucose cotransporter 2 (SGLT2) Successful Target
UniProt ID SC5A2_HUMAN
Gene Name SLC5A2
Synonyms
Solute carrier family 5 member 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter
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Representative Drug(s) Sotagliflozin Drug Info IC50 = 1.5 nM [1]
References  Top
REF 1 Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes. J Med Chem. 2017 May 25;60(10):4173-84.

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