Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T45597 | Target Info | |||
Target Name | Ribosomal protein S6 kinase (S6K) | ||||
Synonyms |
Ribosomal s6 kinase
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Target Type | Clinical trial Target | ||||
Gene Name | NO-GeName | ||||
Biochemical Class | Kinase | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | RAC-alpha serine/threonine-protein kinase (AKT1) | Clinical trial Target | ||||
UniProt ID | AKT1_HUMAN | |||||
Gene Name | AKT1 | |||||
Synonyms |
RAC-PK-alpha; RAC; Proto-oncogene c-Akt; Protein kinase B alpha; PKB alpha
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Representative Drug(s) | XL418 | Drug Info | IC50 = 1 nM | [1] |
References | Top | ||||
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REF 1 | Pyrazolopyrimidines as dual Akt/p70S6K inhibitors. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2693-7. |
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