Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T41515 | Target Info | |||
Target Name | FGFR4 messenger RNA (FGFR4 mRNA) | ||||
Synonyms |
TKF (mRNA); JTK2 (mRNA); FGFR-4 (mRNA); CD334 (mRNA)
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Target Type | Clinical trial Target | ||||
Gene Name | FGFR4 | ||||
Biochemical Class | mRNA target | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Fibroblast growth factor receptor 1 (FGFR1) | Successful Target | ||||
UniProt ID | FGFR1_HUMAN | |||||
Gene Name | FGFR1 | |||||
Synonyms |
c-fgr; bFGF-R-1; bFGF-R; N-sam; HBGFR; Fms-like tyrosine kinase 2; FLT2; FLT-2; FLG; FGFR-1; FGFBR; CEK; CD331 antigen; CD331; Basic fibroblast growth factor receptor 1; BFGFR
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Representative Drug(s) | H3B-6527 | Drug Info | IC50 = 320 nM | [1] |
References | Top | ||||
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REF 1 | Fibroblast Growth Factor Receptor 4 (FGFR4) Selective Inhibitors as Hepatocellular Carcinoma Therapy: Advances and Prospects. J Med Chem. 2019 Mar 28;62(6):2905-2915. |
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