Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T35486 | Target Info | |||
| Target Name | GTPase NRas (NRAS) | ||||
| Synonyms |
Transforming protein N-Ras; HRAS1
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| Target Type | Clinical trial Target | ||||
| Gene Name | NRAS | ||||
| Biochemical Class | Small GTPase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Transformation-sensitive protein p120 (TRPA1) | Successful Target | ||||
| UniProt ID | TRPA1_HUMAN | |||||
| Gene Name | TRPA1 | |||||
| Synonyms |
TRPA1; Ankyrin-like with transmembrane domains protein 1; ANKTM1
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| Representative Drug(s) | Salirasib | Drug Info | EC50 = 800 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | N-Cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites. Eur J Med Chem. 2019 May 15;170:141-156. | ||||
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