Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T35194 Target Info
Target Name Dual specificity protein phosphatase 1 (DUSP1)
Synonyms
VH1; Protein-tyrosine phosphatase CL100; PTPN10; Mitogen-activated protein kinase phosphatase 1; MKP1; MKP-1; MAP kinase phosphatase-1; MAP kinase phosphatase 1; Dual specificity protein phosphatase hVH1; CL100
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Target Type Clinical trial Target
Gene Name DUSP1
Biochemical Class Phosphoric monoester hydrolase
UniProt ID
DUS1_HUMAN
Co-Targets of This Target  Top
Co-Target Name Indoleamine 2,3-dioxygenase 1 (IDO1) Successful Target
UniProt ID I23O1_HUMAN
Gene Name IDO1
Synonyms
Indoleamine-pyrrole 2,3-dioxygenase; INDO; IDO-1; IDO
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Representative Drug(s) Avastin+/-Tarceva Drug Info IC50 = 1000 nM [1]
References  Top
REF 1 Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. J Med Chem. 2008 Mar 27;51(6):1706-18.

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