Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T30374 | Target Info | |||
| Target Name | Gamma-aminobutyric acid uptake (GABAU) | ||||
| Synonyms |
GABA uptake
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | GABA transporter GAT-1 (SLC6A1) | Successful Target | ||||
| UniProt ID | SC6A1_HUMAN | |||||
| Gene Name | SLC6A1 | |||||
| Synonyms |
Solute carrier family 6 member 1; Sodium- and chloride-dependent GABA transporter 1; GAT1; GAT-1; GABT1; GABATR; GABA transporter 1
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| Representative Drug(s) | Tiagabine | Drug Info | Ki = 16.98 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors. Bioorg Med Chem Lett. 2011 Jan 1;21(1):602-5. | ||||
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