Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T29683 | Target Info | |||
| Target Name | Neuromedin-K receptor (TACR3) | ||||
| Synonyms |
Tachykinin receptor 3; TACR3; Neuromedin K receptor; Neurokinin-3 receptor; Neurokinin B receptor; NKR; NK-3R; NK-3 receptor
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| Target Type | Successful Target | ||||
| Gene Name | TACR3 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Substance-K receptor (TACR2) | Clinical trial Target | ||||
| UniProt ID | NK2R_HUMAN | |||||
| Gene Name | TACR2 | |||||
| Synonyms |
Tachykinin receptor 2; Tachykinin neurokinin 2 receptor; TACR2; SKR; Neurokinin A receptor; NK-2R; NK-2 receptor
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| Representative Drug(s) | Talnetant | Drug Info | Ki = 144 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | 2-Phenyl-4-quinolinecarboxamides: a novel class of potent and selective non-peptide competitive antagonists for the human neurokinin-3 receptor. J Med Chem. 1996 Jun 7;39(12):2281-4. | ||||
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