Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T28925 | Target Info | |||
| Target Name | Inosine-5'-monophosphate dehydrogenase (IMPDH) | ||||
| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | Short-chain dehydrogenases reductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Prostaglandin G/H synthase 1 (COX-1) | Successful Target | ||||
| UniProt ID | PGH1_HUMAN | |||||
| Gene Name | PTGS1 | |||||
| Synonyms |
Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PHS 1; PGHS-1; PGH synthase 1; Cyclooxygenase-1; COX1; COX-1
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| Representative Drug(s) | Thioguanine | Drug Info | IC50 = 601 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | DrugMatrix in vitro pharmacology data. National Toxicology Program | ||||
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