Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T27376 Target Info
Target Name GABA(A) receptor delta (GABRD)
Synonyms
Gammaaminobutyric acid receptor subunit delta; GABRD; GABA(A) receptor subunit delta
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Target Type Successful Target
Gene Name GABRD
Biochemical Class Ligand-gated ion channel
UniProt ID
GBRD_HUMAN
Co-Targets of This Target  Top
Co-Target Name GABA A receptor alpha-1/beta-2/gamma-2 (GABRA1/GABRB2/GABRG2) Co-Target
UniProt ID GBRA1_HUMAN-GBRB2_HUMAN-GBRG2_HUMAN
Gene Name GABRA1-GABRB2-GABRG2
Representative Drug(s) Allopregnanolone Drug Info EC50 = 160 nM Click to Show More [1]
2 Allopregnanolone Drug Info EC50 = 160 nM [1]
3 Ganaxolone Drug Info EC50 = 260 nM [1]
4 Ganaxolone Drug Info EC50 = 260 nM [1]
References  Top
REF 1 Synthesis and in vitro activity of 3 beta-substituted-3 alpha-hydroxypregnan-20-ones: allosteric modulators of the GABAA receptor. J Med Chem. 1997 Jan 3;40(1):61-72.

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