Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22032 | Target Info | |||
| Target Name | Parathyroid hormone receptor (PTH2R) | ||||
| Synonyms |
PTHR2; PTH2R; PTH2 receptor
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| Target Type | Clinical trial Target | ||||
| Gene Name | PTH2R | ||||
| Biochemical Class | GPCR secretin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Extracellular calcium-sensing receptor (CASR) | Successful Target | ||||
| UniProt ID | CASR_HUMAN | |||||
| Gene Name | CASR | |||||
| Synonyms |
hCasR; Parathyroid cell calciumreceptor; Parathyroid cell calcium-sensing receptor 1; Parathyroid calcium receptor; Parathyroid Cell calcium-sensing receptor; PCaR1; GPRC2A; CaSR
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| Representative Drug(s) | NPSP-795 | Drug Info | IC50 = 73 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Emerging targets in osteoporosis disease modification. J Med Chem. 2010 Jun 10;53(11):4332-53. | ||||
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