Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T18872 | Target Info | |||
Target Name | Metastasis-suppressor KiSS-1 (KISS1) | ||||
Synonyms |
KiSS-1; KISS1
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Target Type | Clinical trial Target | ||||
Gene Name | KISS1 | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | G-protein coupled receptor 54 (KISS1R) | Discontinued Target | ||||
UniProt ID | KISSR_HUMAN | |||||
Gene Name | KISS1R | |||||
Synonyms |
KiSS-1 receptor GPR54; KISS1R; GPR54
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Representative Drug(s) | TAK-448 | Drug Info | EC50 = 5.2 nM | [1] |
References | Top | ||||
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REF 1 | Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH. J Med Chem. 2016 Oct 13;59(19):8804-11. |
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