Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T12966 | Target Info | |||
| Target Name | Troponin C (TN-C) | ||||
| Synonyms |
Troponin C, slow skeletal and cardiac muscles; TNNC
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| Target Type | Successful Target | ||||
| Gene Name | TNNC1 | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Phosphodiesterase 3 (PDE3) | Successful Target | ||||
| UniProt ID | PDE3A_HUMAN; PDE3B_HUMAN | |||||
| Gene Name | NO-GeName | |||||
| Synonyms |
Phosphodiesterase III; PDE3; Cyclic GMP inhibited phosphodiesterase; Cyclic AMP phosphodiesterase III; CGI-PDE; CAMP phosphodiesterase III
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| Representative Drug(s) | Levosimendan | Drug Info | IC50 = 8 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Stereoselectivity of the positive inotropic effects of newer diazinone-cardiotonics. Bioorg Med Chem Lett. 1994 Nov 10;4(21):2585-8. | ||||
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