Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T11011 | Target Info | |||
| Target Name | Corticotropin-releasing factor receptor 2 (CRHR2) | ||||
| Synonyms |
Corticotropin-releasinghormone receptor 2; CRHR2; CRH2 receptor; CRH-R 2; CRF2; CRF-R 2
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| Target Type | Clinical trial Target | ||||
| Gene Name | CRHR2 | ||||
| Biochemical Class | GPCR secretin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Corticotropin-releasing factor receptor 1 (CRHR1) | Successful Target | ||||
| UniProt ID | CRFR1_HUMAN | |||||
| Gene Name | CRHR1 | |||||
| Synonyms |
Corticotropin-releasing hormone type 1 receptor; Corticotropin-releasing hormone receptor 1; CRHR1; CRH-R 1; CRF1; CRF-R1; CRF-R; CRF-1 receptor; CRF receptor
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| Representative Drug(s) | NBI-34041 | Drug Info | Ki = 4 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. J Med Chem. 2011 Jun 23;54(12):4187-206. | ||||
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