Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T03410 | Target Info | |||
| Target Name | Mycobacterium Membrane protein mmpL3 (MycB mmpL3) | ||||
| Synonyms |
Trehalose monomycolate exporter MmpL3; TMM exporter MmpL3
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| Target Type | Clinical trial Target | ||||
| Gene Name | MycB mmpL3 | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Squalene synthetase (FDFT1) | Discontinued Target | ||||
| UniProt ID | FDFT_HUMAN | |||||
| Gene Name | FDFT1 | |||||
| Synonyms |
Squalene synthase; SS; SQS; Farnesyl-diphosphate farnesyltransferase; FPP:FPP farnesyltransferase
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| Representative Drug(s) | SQ-109 | Drug Info | Ki = 740 nM | [1] | ||
| Co-Target Name | Staphylococcus Dehydrosqualene synthase (Stap-coc crtM) | Co-Target | ||||
| UniProt ID | CRTM_STAAU | |||||
| Gene Name | crtM | |||||
| Synonyms |
Staphylococcus 4,4'-diapophytoene synthase; Staphylococcus DAP synthase; Staphylococcus C30 carotenoid synthase
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| Representative Drug(s) | SQ-109 | Drug Info | Ki = 360 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Head-to-head prenyl tranferases: anti-infective drug targets. J Med Chem. 2012 May 10;55(9):4367-72. | ||||
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