| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T03346 | ||||
| Target Name | Interleukin-4 receptor alpha chain | ||||
| Target Type | Successful |
||||
| Action against Disease Model | PRX-321 | PRX321 was specifically and highly cytotoxic IC50 ranging from >0.1 to 13 ng/mL] to six of eight pancreatic cancer cell | Drug Info | ||
| The Effect of Target Knockout, Knockdown or Genetic Variations | Gene deletion resulted in Eosinophilia,Remodelling and Immune response decrease compared to wild type | ||||
| References | |||||
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