| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T43830 | ||||
| Target Name | 5-hydroxytryptamine 2 receptor | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Mianserin | Drug Info | IC50 = 1703 nM | [552194] | |
| Ketanserin | Drug Info | Ki = 3.5 nM | [552297] | ||
| References | |||||
| Ref 552194 | Binding affinity of sarpogrelate to 5-HT(2A) receptor ligand recognition sites in rat renal cortical and mesangial cells in culture. Gen Pharmacol. 1999 Jul;33(1):51-7. | ||||
| Ref 552297 | Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists. Curr Top Med Chem. 2002 Jun;2(6):539-58. | ||||
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