| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T43721 | ||||
| Target Name | Corticosteroid 11-beta-dehydrogenase, isozyme 2 | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | GLYCYRRHIZIN | Drug Info | IC50 = 1 nM | [530241] | |
| References | |||||
| Ref 530241 | Bioorg Med Chem Lett. 2009 Aug 1;19(15):4455-8. Epub 2009 May 15.4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice. | ||||
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