| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T98315 | ||||
| Target Name | mRNA of human acyl CoA cholesterol acyl-transferase-2 | ||||
| Target Type | Research |
||||
| Drug Potency against Target | PYRIPYROPENE A | Drug Info | IC50 = 640 nM | [527340] | |
| Oleic acid anilide | Drug Info | IC50 = 170 nM | [528385] | ||
| References | |||||
| Ref 527340 | Bioorg Med Chem Lett. 2005 Jan 17;15(2):385-8.Saucerneol B derivatives as human acyl-CoA: cholesterol acyltransferase inhibitors. | ||||
| Ref 528385 | Bioorg Med Chem Lett. 2006 Nov 1;16(21):5580-3. Epub 2006 Aug 21.Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata. | ||||
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