| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T15497 | ||||
| Target Name | Prostaglandin E2 receptor, EP1 subtype | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | LAROPIPRANT | Drug Info | Ki = 1160 nM | [528672] | |
| References | |||||
| Ref 528672 | J Med Chem. 2007 Feb 22;50(4):794-806.Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524). | ||||
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