Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E4GM
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| Former ID |
DNC007145
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| Drug Name |
3-isopr-sal-cyclosal-d4TMP
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| Synonyms |
CHEMBL375636; 3-isopr-sal-cyclosal-d4TMP; (Sp)-3-isopr-sal-cyclosal-d4TMP; (Rp)-3-isopr-sal-cyclosal-d4TMP; BDBM50206632; 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-5-[[[8-(2,2-dimethyl-4H-1,3-benzodioxin-8-yl)-2-oxido-4H-1,3,2-benzodioxaphosphorin-2-yl]oxy]methyl]-2,5-dihydro-2-furanyl]-5-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C27H27N2O9P
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| Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2C=CC(O2)COP3(=O)OCC4=C(O3)C(=CC=C4)C5=CC=CC6=C5OC(OC6)(C)C
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| InChI |
1S/C27H27N2O9P/c1-16-12-29(26(31)28-25(16)30)22-11-10-19(36-22)15-35-39(32)34-14-18-7-5-9-21(24(18)38-39)20-8-4-6-17-13-33-27(2,3)37-23(17)20/h4-12,19,22H,13-15H2,1-3H3,(H,28,30,31)/t19-,22+,39?/m0/s1
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| InChIKey |
CCBOYGOTQIYLJA-CATCILLUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides. J Med Chem. 2007 Mar 22;50(6):1335-46. | |||
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