Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09OPL
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| Former ID |
DNC010568
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| Drug Name |
(1'H-Phenothiazin-1'-yl)(piperidin-1-yl)methanone
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| Synonyms |
CHEMBL589252; Phenothiazin-10-yl-piperidin-1-yl-methanone; AC1LE3IL; ChemDiv3_004237; Oprea1_668518; ZINC91249; MolPort-001-995-166; HMS1485A13; STK004206; BDBM50308415; AKOS000643159; CCG-113845; MCULE-9139922844; IDI1_022147; BAS 04087808; phenothiazin-10-yl(piperidin-1-yl)methanone; SR-01000506180; 10H-phenothiazin-10-yl(piperidin-1-yl)methanone; SR-01000506180-1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H18N2OS
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| Canonical SMILES |
C1CCN(CC1)C(=O)N2C3=CC=CC=C3SC4=CC=CC=C42
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| InChI |
1S/C18H18N2OS/c21-18(19-12-6-1-7-13-19)20-14-8-2-4-10-16(14)22-17-11-5-3-9-15(17)20/h2-5,8-11H,1,6-7,12-13H2
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| InChIKey |
ZYAXTAFPNAMCKA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Bioorg Med Chem. 2010 Mar 15;18(6):2232-2244. | |||
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