TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T99616	Trypanosoma Trypanothione reductase	B1IL2G	Methyl (2,6-dimethyl-4-phenylquinazolin-3(4H)-yl)acetate	Investigative	2870319	C19H20N2O2	308.4	CC1=CC2=C(C=C1)N=C(N(C2C3=CC=CC=C3)CC(=O)OC)C	IC50 = 67000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B2XN4M	N-Acetylphenoxazine	Investigative	3304561	C14H11NO2	225.24	CC(=O)N1C2=CC=CC=C2OC3=CC=CC=C31	IC50 ~ 100000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B47XHW	3-(8-Bromo-6-chloro-2-methyl-4-phenyl-4H-quinazolin-3-yl)-N,N-dimethylpropan-1-amine	Investigative	54757489	C20H23BrClN3	420.8	CC1=NC2=C(C=C(C=C2Br)Cl)C(N1CCCN(C)C)C3=CC=CC=C3	IC50 = 53000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B5C1UD	Methyl [6-bromo-4-(2-chlorophenyl)-2-methylquinazolin-3(4H)-yl]acetate	Investigative	3117554	C18H16BrClN2O2	407.7	CC1=NC2=C(C=C(C=C2)Br)C(N1CC(=O)OC)C3=CC=CC=C3Cl	IC50 ~ 100000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B65ONY	Methyl 2-[6-bromo-2-(2-morpholin-4-ylethyl)-4-phenyl-4H-quinazolin-3-yl]acetate	Investigative	3119180	C23H26BrN3O3	472.4	COC(=O)CN1C(C2=C(C=CC(=C2)Br)N=C1CCN3CCOCC3)C4=CC=CC=C4	IC50 = 93000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B98WSG	1-(4-Chlorophenyl)-3-morpholin-4-ylpropan-1-one	Investigative	723918	C13H16ClNO2	253.72	C1COCCN1CCC(=O)C2=CC=C(C=C2)Cl	IC50 = 148000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	B9T4DH	1-(3,4-Dichlorophenyl)-3-(4-ethylanilino)-1-propanone	Investigative	831028	C17H17Cl2NO	322.2	CCC1=CC=C(C=C1)NCCC(=O)C2=CC(=C(C=C2)Cl)Cl	IC50 = 107000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	BH0QI9	2-Chloro-10H-phenoxazine	Investigative	10632580	C12H8ClNO	217.65	C1=CC=C2C(=C1)NC3=C(O2)C=CC(=C3)Cl	IC50 = 69200 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	BIW29M	4-Benzyl-6-chloro-2-methyl-3-(2-piperidin-1-ylethyl)-4H-quinazoline	Investigative	54757594	C23H28ClN3	381.9	CC1=NC2=C(C=C(C=C2)Cl)C(N1CCN3CCCCC3)CC4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	BN7SU4	(6-Methyl-2,4-diphenyl-4H-quinazolin-3-yl)-acetic acid methyl ester	Investigative	3123254	C24H22N2O2	370.4	CC1=CC2=C(C=C1)N=C(N(C2C3=CC=CC=C3)CC(=O)OC)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	BR18WU	Methyl [6-methyl-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]acetate	Investigative	2870365	C27H28N2O5	460.5	CC1=CC2=C(C=C1)N=C(N(C2C3=CC=CC=C3)CC(=O)OC)C4=CC(=C(C(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T99616	Trypanosoma Trypanothione reductase	BX0Y1J	Methyl [6-bromo-2-(morpholin-4-ylmethyl)-4-phenylquinazolin-3(4H)-yl]acetate	Investigative	2870470	C22H24BrN3O3	458.3	COC(=O)CN1C(C2=C(C=CC(=C2)Br)N=C1CN3CCOCC3)C4=CC=CC=C4	IC50 = 89000 nM	Poor binder