TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T99455	HUMAN fusion protein Bcr-Abl	B3EX0U	N-[2-[[4-(3-Amino-1H-indazol-4-yl)benzoyl]amino]ethyl]-2-methoxybenzamide	Investigative	122196202	C24H23N5O3	429.5	COC1=CC=CC=C1C(=O)NCCNC(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B3U1ZK	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(3,5-dimethoxybenzoyl)piperazin-1-yl]methanone	Investigative	122196189	C27H27N5O4	485.5	COC1=CC(=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B3VU6W	N-[2-[[4-(3-Amino-1H-indazol-4-yl)benzoyl]amino]ethyl]-3-(trifluoromethyl)benzamide	Investigative	122196200	C24H20F3N5O2	467.4	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NCCNC(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N	IC50 = 56270 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B3ZLF2	4-(4-Methylphenyl)-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine	Investigative	73351906	C19H15F4N3O	377.3	CC1=CC=C(C=C1)C2=NC(=NC=C2)NC3=CC(=CC=C3)OC(C(F)F)(F)F	IC50 = 50118.72 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B4W5EY	[4-(2-Fluorobenzoyl)piperazin-1-yl]-[4-[6-[4-(trifluoromethyl)anilino]pyrimidin-4-yl]phenyl]methanone	Investigative	118722069	C29H23F4N5O2	549.5	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=CC(=NC=N3)NC4=CC=C(C=C4)C(F)(F)F)C(=O)C5=CC=CC=C5F	IC50 = 78600 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B68CGO	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(2-methoxybenzoyl)piperazin-1-yl]methanone	Investigative	122196195	C26H25N5O3	455.5	COC1=CC=CC=C1C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B6J9NQ	4-Pyridin-4-yl-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrimidin-2-amine	Investigative	9799152	C17H12F4N4O	364.3	C1=CC(=CC(=C1)OC(C(F)F)(F)F)NC2=NC=CC(=N2)C3=CC=NC=C3	IC50 = 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B6N9JD	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(2-methylbenzoyl)piperazin-1-yl]methanone	Investigative	122196196	C26H25N5O2	439.5	CC1=CC=CC=C1C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B6QWJ4	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(4-methoxybenzoyl)piperazin-1-yl]methanone	Investigative	122196192	C26H25N5O3	455.5	COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B87MSV	[4-[6-(3-Chloroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone	Investigative	118722086	C28H23ClFN5O2	516	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=CC(=NC=N3)NC4=CC(=CC=C4)Cl)C(=O)C5=CC=CC=C5F	IC50 = 91800 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B8SO6Y	N-[2-[[4-(3-Amino-1H-indazol-4-yl)benzoyl]amino]ethyl]-3-fluorobenzamide	Investigative	122196201	C23H20FN5O2	417.4	C1=CC(=CC(=C1)F)C(=O)NCCNC(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	B9VF8A	[4-[6-(2-Chloroanilino)pyrimidin-4-yl]phenyl]-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone	Investigative	118722074	C28H23ClFN5O2	516	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=CC(=NC=N3)NC4=CC=CC=C4Cl)C(=O)C5=CC=CC=C5F	IC50 = 141000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BACZ82	[4-[3-(Dimethylamino)benzoyl]piperazin-1-yl]-[4-[6-(4-methoxyanilino)pyrimidin-4-yl]phenyl]methanone	Investigative	122190873	C31H32N6O3	536.6	CN(C)C1=CC=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=CC(=NC=N4)NC5=CC=C(C=C5)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BBG64C	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(3-methylbenzoyl)piperazin-1-yl]methanone	Investigative	122196193	C26H25N5O2	439.5	CC1=CC(=CC=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BBG8S9	[4-[6-(4-Methoxyanilino)pyrimidin-4-yl]phenyl]-[4-(4-methoxybenzoyl)piperazin-1-yl]methanone	Investigative	122190867	C30H29N5O4	523.6	COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=CC(=NC=N4)NC5=CC=C(C=C5)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BD0AT7	N-[2-[[4-(3-Amino-1H-indazol-4-yl)benzoyl]amino]ethyl]-3,4-difluorobenzamide	Investigative	122196197	C23H19F2N5O2	435.4	C1=CC(=C2C(=C1)NN=C2N)C3=CC=C(C=C3)C(=O)NCCNC(=O)C4=CC(=C(C=C4)F)F	IC50 = 75290 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BD1H6M	[4-(3-Fluorobenzoyl)piperazin-1-yl]-[4-(4-methylpyridin-2-yl)phenyl]methanone	Investigative	122189051	C24H22FN3O2	403.4	CC1=CC(=NC=C1)C2=CC=C(C=C2)C(=O)N3CCN(CC3)C(=O)C4=CC(=CC=C4)F	IC50 = 63300 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BDBZ42	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl]methanone	Investigative	122196190	C26H22F3N5O2	493.5	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N)C(=O)C5=CC(=CC=C5)C(F)(F)F	IC50 = 94570 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BEM42G	4-Amino-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide	Investigative	44340726	C23H20N6O	396.4	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)N)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 = 67608.3 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BI8BX3	[4-(3-Methoxybenzoyl)piperazin-1-yl]-(4-thiophen-2-ylphenyl)methanone	Investigative	122189060	C23H22N2O3S	406.5	COC1=CC=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=CC=CS4	IC50 = 89700 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BIH86Z	5-Bromo-2-chloro-4-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]pyrimidine	Investigative	134131688	C14H13BrClFN4O2S	435.7	C1CN(CCN1C2=NC(=NC=C2Br)Cl)S(=O)(=O)C3=CC=C(C=C3)F	IC50 = 122000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BJ7TS8	[4-[6-(4-Methoxyanilino)pyrimidin-4-yl]phenyl]-[4-(3-methylbenzoyl)piperazin-1-yl]methanone	Investigative	122190872	C30H29N5O3	507.6	CC1=CC(=CC=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=CC(=NC=N4)NC5=CC=C(C=C5)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BMI10Z	(E)-3,5-Di-tert-butyl-3',5'-dimethoxystilbene-4-ol	Investigative	11199480	C24H32O3	368.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C/C2=CC(=CC(=C2)OC)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BN0PL2	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(3-methoxybenzoyl)piperazin-1-yl]methanone	Investigative	122196085	C26H25N5O3	455.5	COC1=CC=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=C5C(=CC=C4)NN=C5N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BN0Z6P	[4-[6-(4-Methoxyanilino)pyrimidin-4-yl]phenyl]-[4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl]methanone	Investigative	122190871	C30H26F3N5O3	561.6	COC1=CC=C(C=C1)NC2=NC=NC(=C2)C3=CC=C(C=C3)C(=O)N4CCN(CC4)C(=O)C5=CC(=CC=C5)C(F)(F)F	IC50 = 51920 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BN56BV	2-(3,5-Dimethoxy-phenyl)-6-methoxy-naphthalene	Investigative	11687939	C19H18O3	294.3	COC1=CC2=C(C=C1)C=C(C=C2)C3=CC(=CC(=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BN58LP	N-[2-[(4-Tert-butylbenzoyl)amino]ethyl]-4-[6-(4-methoxyanilino)pyrimidin-4-yl]benzamide	Investigative	122190823	C31H33N5O3	523.6	CC(C)(C)C1=CC=C(C=C1)C(=O)NCCNC(=O)C2=CC=C(C=C2)C3=CC(=NC=N3)NC4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BP0HD2	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(4-chlorobenzoyl)piperazin-1-yl]methanone	Investigative	122196194	C25H22ClN5O2	459.9	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N)C(=O)C5=CC=C(C=C5)Cl	IC50 = 65630 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BQ40PL	1,3-Dimethoxy-5-[4-(4-methoxyphenyl)phenyl]benzene	Investigative	11709536	C21H20O3	320.4	COC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC(=CC(=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BR4X5J	(3-Nitro-phenyl)-(4-pyridin-4-yl-pyrimidin-2-yl)-amine	Investigative	9814609	C15H11N5O2	293.28	C1=CC(=CC(=C1)[N+](=O)[O-])NC2=NC=CC(=N2)C3=CC=NC=C3	IC50 = 61659.5 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BT4J7L	4-(3-Amino-1H-indazol-4-yl)-N-[2-[(4-methoxybenzoyl)amino]ethyl]benzamide	Investigative	122196203	C24H23N5O3	429.5	COC1=CC=C(C=C1)C(=O)NCCNC(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N	IC50 ~ 100000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BU1QG7	[4-(3-Amino-1H-indazol-4-yl)phenyl]-[4-(3,4-difluorobenzoyl)piperazin-1-yl]methanone	Investigative	122196191	C25H21F2N5O2	461.5	C1CN(CCN1C(=O)C2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N)C(=O)C5=CC(=C(C=C5)F)F	IC50 = 83520 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BVI2B4	[4-(3-Methoxybenzoyl)piperazin-1-yl]-(4-pyridin-3-ylphenyl)methanone	Investigative	122189048	C24H23N3O3	401.5	COC1=CC=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=CN=CC=C4	IC50 = 60670 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BX9CF3	5-Bromo-2-chloro-4-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]pyrimidine	Investigative	134137546	C15H16BrClN4O2S	431.7	CC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C3=NC(=NC=C3Br)Cl	IC50 = 58000 nM	Poor binder
T99455	HUMAN fusion protein Bcr-Abl	BZ50MI	[4-(2-Chlorobenzoyl)piperazin-1-yl]-[4-[6-(4-methoxyanilino)pyrimidin-4-yl]phenyl]methanone	Investigative	122190831	C29H26ClN5O3	528	COC1=CC=C(C=C1)NC2=NC=NC(=C2)C3=CC=C(C=C3)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5Cl	IC50 = 73910 nM	Poor binder