TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98945	HUMAN dibasic-processing enzyme	B2G5UK	[(1S,2S,4R,5R)-2,4-Bis(diaminomethylideneamino)-5-[[2-(diaminomethylideneamino)phenyl]carbamoyloxy]cyclohexyl] N-[2-(diaminomethylideneamino)phenyl]carbamate	Investigative	44593199	C24H34N14O4	582.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC(=O)NC2=CC=CC=C2N=C(N)N)OC(=O)NC3=CC=CC=C3N=C(N)N)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	B3X1LZ	N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232269	C8H9N5O3S3	319.4	COCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	B49BPE	Triazole, 7b	Investigative	42618077	C16H10Cl2N6O2S2	453.3	CN1C=CC=C1C2=NN=C(N2C3=C(C=C(C=C3)Cl)Cl)SC4=NC=C(S4)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	B4P9TV	N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232270	C15H15N5O4S3	425.5	COC1=C(C=C(C=C1)CCNC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])OC	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	B78APL	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(3-guanidino-pyridin-4-yloxy)-cyclohexyl]-guanidine	Investigative	44593175	C20H30N14O2	498.5	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=C(C=NC=C2)N=C(N)N)OC3=C(C=NC=C3)N=C(N)N)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	B7GVJ1	5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3,4-thiadiazol-2-amine	Investigative	46232267	C8H9N5O2S3	303.4	CCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BF0W8I	N-Sec-Butyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232312	C9H11N5O2S3	317.4	CCC(C)NC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BFR0K8	2-[(1S,2S,4R,5R)-2,4-Bis[(2-amino-3H-benzimidazol-5-yl)oxy]-5-(diaminomethylideneamino)cyclohexyl]guanidine	Investigative	44593197	C22H28N12O2	492.5	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC3=C(C=C2)N=C(N3)N)OC4=CC5=C(C=C4)N=C(N5)N)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BGYK42	Triazole, 3j	Investigative	25196726	C11H6N6O5S2	366.3	C1=CC(=CC=C1N2C(=O)NN=C2SC3=NC=C(S3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BK21VN	Halicin	Investigative	11837140	C5H3N5O2S3	261.3	C1=C(SC(=N1)SC2=NN=C(S2)N)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BO8K3Q	5-Methoxy-2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole	Investigative	44156975	C11H7N3O3S3	325.4	COC1=CC2=C(C=C1)SC(=N2)SC3=NC=C(S3)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BQKZ15	{[4-(N''-Carbamimidoylhydrazinecarbonyl)phenyl]formohydrazido}methanimidamide	Investigative	53321290	C10H14N8O2	278.27	C1=CC(=CC=C1C(=O)NN=C(N)N)C(=O)NN=C(N)N	Ki = 173000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BS8DZ7	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(3-guanidino-pyridin-2-yloxy)-cyclohexyl]-guanidine	Investigative	44593174	C20H30N14O2	498.5	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=C(C=CC=N2)N=C(N)N)OC3=C(C=CC=N3)N=C(N)N)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BVC4O1	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(2-guanidino-phenoxy)-cyclohexyl]-guanidine	Investigative	44593173	C22H32N12O2	496.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC=CC=C2N=C(N)N)OC3=CC=CC=C3N=C(N)N)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BVCX25	2-[(1R,2R,4S,5S)-5-(Diaminomethylideneamino)-2,4-dipyridin-2-yloxycyclohexyl]guanidine	Investigative	44593198	C18H24N8O2	384.4	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC=CC=N2)OC3=CC=CC=N3)N=C(N)N	Ki = 100000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BW3U0R	2-(5-Nitrothiazol-2-ylthio)benzo[d]thiazole	Investigative	44156976	C10H5N3O2S3	295.4	C1=CC=C2C(=C1)N=C(S2)SC3=NC=C(S3)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T98945	HUMAN dibasic-processing enzyme	BX4BY3	Dithioether 1,3,4-thiadiazole, 8f	Investigative	20333093	C8H2N6O4S5	406.5	C1=C(SC(=N1)SC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder