TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98278	HUMAN type-1 angiotensin II receptor	B02TEJ	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 5-chloro-2-nitrobenzoate	Investigative	18572335	C18H12ClN3O6S	433.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=C(C=CC(=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B0LZQ5	[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-nitrobenzenesulfonate	Investigative	49787115	C18H15N3O7S2	449.5	CC1=CC(=NC(=N1)SCC2=CC(=O)C(=CO2)OS(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-])C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B0UMG3	5-Hydroxy-2-((phenylthio)methyl)-4H-pyran-4-one	Investigative	44726831	C12H10O3S	234.27	C1=CC=C(C=C1)SCC2=CC(=O)C(=CO2)O	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B1GQ3B	4-Methyl-3-nitrobenzoic acid [6-[[(4-methyl-2-pyrimidinyl)thio]methyl]-4-oxo-3-pyranyl] ester	Investigative	7217947	C19H15N3O6S	413.4	CC1=C(C=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC(=N3)C)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B1IW9B	[4-Oxo-6-[[4-(trifluoromethoxy)phenyl]sulfanylmethyl]pyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	49842899	C20H11ClF3NO7S	501.8	C1=CC(=CC=C1OC(F)(F)F)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B1JN3L	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-chlorobenzoate	Investigative	7217922	C18H13ClN2O4S	388.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B1ZKR6	4-Cyanobenzoic acid [6-[[(4-methyl-2-pyrimidinyl)thio]methyl]-4-oxo-3-pyranyl] ester	Investigative	46905018	C19H13N3O4S	379.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)C#N	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B28OLN	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-chloro-3-nitrobenzoate	Investigative	18572338	C17H10ClN3O6S	419.8	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B2GBE1	[6-[(4-Methoxyphenyl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	49842903	C20H14ClNO7S	447.8	COC1=CC=C(C=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B2WEA3	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-chlorobenzoate	Investigative	7217921	C17H11ClN2O4S	374.8	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B3MF2O	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-ethoxybenzoate	Investigative	7217884	C19H16N2O5S	384.4	CCOC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B3R4UN	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-cyanobenzoate	Investigative	49787120	C19H13N3O4S	379.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=CC(=C3)C#N	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B3VM2X	4-Methyl-3-nitrobenzoic acid [4-oxo-6-[(2-pyrimidinylthio)methyl]-3-pyranyl] ester	Investigative	7217946	C18H13N3O6S	399.4	CC1=C(C=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B40KWY	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-butoxybenzoate	Investigative	7217891	C21H20N2O5S	412.5	CCCCOC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B43AZJ	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-methylbenzoate	Investigative	7217861	C18H14N2O4S	354.4	CC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B48YBW	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-isopropoxybenzoate	Investigative	7217887	C20H18N2O5S	398.4	CC(C)OC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B4FE7N	5-Hydroxy-2-((pyrimidin-2-ylthio)methyl)-4H-pyran-4-one	Investigative	42281625	C10H8N2O3S	236.25	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)O	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B4HY9T	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2-methyl-3-nitrobenzoate	Investigative	7217944	C18H13N3O6S	399.4	CC1=C(C=CC=C1[N+](=O)[O-])C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B4NW8Q	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl furan-2-carboxylate	Investigative	7218011	C16H12N2O5S	344.3	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=CO3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B4VWR9	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 3-methoxybenzoate	Investigative	7217876	C19H16N2O5S	384.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=CC=C3)OC	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B5RSD7	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 3-chlorobenzoate	Investigative	7217919	C18H13ClN2O4S	388.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=CC=C3)Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B69VHK	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(morpholinosulfonyl)benzoate	Investigative	18572382	C21H19N3O7S2	489.5	C1COCCN1S(=O)(=O)C2=CC=C(C=C2)C(=O)OC3=COC(=CC3=O)CSC4=NC=CC=N4	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B6AOL1	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2-chloro-5-nitrobenzoate	Investigative	18572337	C17H10ClN3O6S	419.8	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=C(C=CC(=C3)[N+](=O)[O-])Cl	IC50 = 60100 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B7I8OF	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] thiophene-3-carboxylate	Investigative	71462076	C16H12N2O4S2	360.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CSC=C3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B7INW0	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-(trifluoromethyl)benzoate	Investigative	18572343	C19H13F3N2O4S	422.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B7Y6DH	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 1,3-oxazole-5-carboxylate	Investigative	71456693	C15H11N3O5S	345.3	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CN=CO3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B83PJL	[6-[(4-Chlorophenyl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	49842902	C19H11Cl2NO6S	452.3	C1=CC(=CC=C1SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-])Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B8ERY4	Apelin precursor (61-77) (human, bovine, mouse, rat) trifluoroacetate	Investigative	16130452	C96H156N34O20S	2138.6	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC6=CC=CC=C6)NC(=O)[C@H](CCCCN)N	Ki ~ 100000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B8FQ5H	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-(trifluoromethoxy)benzoate	Investigative	46905020	C19H13F3N2O5S	438.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)OC(F)(F)F	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B8PV4K	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-fluorobenzoate	Investigative	7217913	C18H13FN2O4S	372.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)F	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B8W1RQ	4-Cyanobenzoic acid [4-oxo-6-[(2-pyrimidinylthio)methyl]-3-pyranyl] ester	Investigative	46905029	C18H11N3O4S	365.4	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)C#N	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B8W7CB	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-(pyrrolidin-1-ylsulfonyl)benzoate	Investigative	12005825	C22H21N3O6S2	487.6	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)S(=O)(=O)N4CCCC4	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B98LEN	[4-Oxo-6-(phenylsulfanylmethyl)pyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	46905028	C19H12ClNO6S	417.8	C1=CC=C(C=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B9CYW7	[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] benzenesulfonate	Investigative	49787117	C18H16N2O5S2	404.5	CC1=CC(=NC(=N1)SCC2=CC(=O)C(=CO2)OS(=O)(=O)C3=CC=CC=C3)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	B9Z5SM	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl [1,1'-biphenyl]-4-carboxylate	Investigative	18572352	C23H16N2O4S	416.5	C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)OC3=COC(=CC3=O)CSC4=NC=CC=N4	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BAO16P	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 3-methylbenzoate	Investigative	7217859	C19H16N2O4S	368.4	CC1=CC(=CC=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC(=N3)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BB3OR8	[6-[(4-Methylphenyl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	49842905	C20H14ClNO6S	431.8	CC1=CC=C(C=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BBJ93P	[6-[(4-Methylpyrimidin-2-yl)sulfonylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	46905034	C18H12ClN3O8S	465.8	CC1=NC(=NC=C1)S(=O)(=O)CC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BC70DS	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl benzoate	Investigative	7217852	C17H12N2O4S	340.4	C1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BCX39O	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(N,N-dimethylsulfamoyl)benzoate	Investigative	16194671	C19H17N3O6S2	447.5	CN(C)S(=O)(=O)C1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BE75RM	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 5-nitrofuran-2-carboxylate	Investigative	46905022	C16H11N3O7S	389.3	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(O3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BEO0G5	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-methylbenzoate	Investigative	7217856	C19H16N2O4S	368.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=CC=C3C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BEU81N	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 3-nitrobenzoate	Investigative	7217938	C17H11N3O6S	385.4	C1=CC(=CC(=C1)[N+](=O)[O-])C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BF73VM	2-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-5-hydroxy-4H-pyran-4-one	Investigative	46835120	C12H12N2O3S	264.3	CC1=CC(=NC(=N1)SCC2=CC(=O)C(=CO2)O)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BFE29Z	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 3,4-dimethylbenzoate	Investigative	7217867	C19H16N2O4S	368.4	CC1=C(C=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BFRN42	5-[(4-Chloro-3-nitrophenyl)methoxy]-2-[(4-methylpyrimidin-2-yl)sulfanylmethyl]pyran-4-one	Investigative	46905038	C18H14ClN3O5S	419.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OCC3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BFVH97	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-fluorobenzoate	Investigative	7217912	C17H11FN2O4S	358.3	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)F	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BGPJ87	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(N,N-diethylsulfamoyl)benzoate	Investigative	18572378	C21H21N3O6S2	475.5	CCN(CC)S(=O)(=O)C1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BH04BO	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2,2-dimethylpropanoate	Investigative	46905014	C16H18N2O4S	334.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C(C)(C)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BH1MC3	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(trifluoromethyl)benzoate	Investigative	7217950	C18H11F3N2O4S	408.4	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BH2XV6	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-bromobenzoate	Investigative	16805942	C17H11BrN2O4S	419.3	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)Br	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BHB6Y9	N-[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl]benzamide	Investigative	49787119	C18H15N3O3S	353.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)NC(=O)C3=CC=CC=C3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BI1BH2	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 5-chloro-2-nitrobenzoate	Investigative	18572334	C17H10ClN3O6S	419.8	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=C(C=CC(=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BIL39K	4-Nitrobenzoic acid [6-[[(4-methyl-2-pyrimidinyl)thio]methyl]-4-oxo-3-pyranyl] ester	Investigative	7217942	C18H13N3O6S	399.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BIV28B	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(piperidin-1-ylsulfonyl)benzoate	Investigative	18572379	C22H21N3O6S2	487.6	C1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C(=O)OC3=COC(=CC3=O)CSC4=NC=CC=N4	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BJ87PZ	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 3-nitrobenzoate	Investigative	7217939	C18H13N3O6S	399.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=CC=C3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BJA4K5	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chlorobenzoate	Investigative	7217916	C18H13ClN2O4S	388.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=CC=C3Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BKU97C	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-methoxybenzoate	Investigative	7217878	C18H14N2O5S	370.4	COC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BL48RV	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-methylpropanoate	Investigative	46905037	C15H16N2O4S	320.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C(C)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BN7YA0	2-(((4-Fluorophenyl)thio)methyl)-5-hydroxy-4H-pyran-4-one	Investigative	351037	C12H9FO3S	252.26	C1=CC(=CC=C1F)SCC2=CC(=O)C(=CO2)O	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BNG13V	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-methoxybenzoate	Investigative	7217879	C19H16N2O5S	384.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)OC	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BQ5IT1	N-[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl]-4-nitrobenzamide	Investigative	49842908	C18H14N4O5S	398.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BQM95X	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] acetate	Investigative	46905025	C13H12N2O4S	292.31	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BS9V8A	2-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-5-phenylmethoxypyran-4-one	Investigative	46835118	C18H16N2O3S	340.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OCC3=CC=CC=C3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BSA01E	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chloro-5-nitrobenzoate	Investigative	12005898	C18H12ClN3O6S	433.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=C(C=CC(=C3)[N+](=O)[O-])Cl	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BSRM25	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-methylbenzoate	Investigative	7217862	C19H16N2O4S	368.4	CC1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC(=N3)C	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BT7AO9	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(tert-butyl)benzoate	Investigative	7217870	C21H20N2O4S	396.5	CC(C)(C)C1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BV1TG8	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4,5-dimethoxy-2-nitrobenzoate	Investigative	18572395	C19H15N3O8S	445.4	COC1=C(C=C(C(=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3)[N+](=O)[O-])OC	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BVAR24	5-Hydroxy-2-(((4-methylpyrimidin-2-yl)thio)methyl)-4H-pyran-4-one	Investigative	46835124	C11H10N2O3S	250.28	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)O	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BVL9I3	(6S)-1-[(4-Amino-3-methylphenyl)methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid	Investigative	5311348	C29H28N4O3	480.6	CC1=C(C=CC(=C1)CN2C=NC3=C2C[C@H](N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BW4NJ7	[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate	Investigative	12005992	C18H12ClN3O6S	433.8	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BX15IC	6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl benzoate	Investigative	7217853	C18H14N2O4S	354.4	CC1=NC(=NC=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=CC=C3	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	BYW32L	4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(pyrrolidin-1-ylsulfonyl)benzoate	Investigative	16832372	C21H19N3O6S2	473.5	C1CCN(C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)OC3=COC(=CC3=O)CSC4=NC=CC=N4	IC50 ~ 79000 nM	Poor binder
T98278	HUMAN type-1 angiotensin II receptor	D05NXX	ML221	Investigative	7217941	C17H11N3O6S	385.4	C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 79000 nM	Poor binder