TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98269	Caspase-1	B0HO7D	3-(Benzyloxycarbonylamino)-4-oxo-5-(1-naphthylsulfonylamino)pentanoic acid	Investigative	18354267	C23H22N2O7S	470.5	C1=CC=C(C=C1)COC(=O)NC(CC(=O)O)C(=O)CNS(=O)(=O)C2=CC=CC3=CC=CC=C32	IC50 = 174000 nM	Poor binder
T98269	Caspase-1	B1JPL8	3-Allyloxycarbonylamino-5-(methyl-phenethyl-amino)-4-oxo-pentanoic acid	Investigative	44279695	C18H24N2O5	348.4	CN(CCC1=CC=CC=C1)CC(=O)[C@H](CC(=O)O)NC(=O)OCC=C	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	B23XHA	3-Allyloxycarbonylamino-5-(benzhydryl-amino)-4-oxo-pentanoic acid	Investigative	44279669	C22H24N2O5	396.4	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CNC(C1=CC=CC=C1)C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	B29YTW	2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-methyl-butyl)-3-methyl-butyramide	Investigative	10861643	C17H25FN2O4S	372.5	CC(C)C[C@H](C=O)NC(=O)[C@H](C(C)C)NS(=O)(=O)C1=CC=C(C=C1)F	IC50 ~ 100000 nM	Poor binder
T98269	Caspase-1	B3A4OC	3-(Benzyloxycarbonylamino)-4-oxo-5-[2-(1-naphthyl)ethylsulfonylamino]pentanoic acid	Investigative	18354276	C25H26N2O7S	498.5	C1=CC=C(C=C1)COC(=O)NC(CC(=O)O)C(=O)CNS(=O)(=O)CCC2=CC=CC3=CC=CC=C32	IC50 = 55600 nM	Poor binder
T98269	Caspase-1	B3CA8I	(s)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxymethylpyrrolidine-1-sulfonyl)-1h-indole-2,3-dione	Investigative	11533326	C25H22FN3O5S	495.5	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CN=C(C=C4)F)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	B3X4UN	3-Allyloxycarbonylamino-5-benzylamino-4-oxo-pentanoic acid	Investigative	44279683	C16H20N2O5	320.34	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CNCC1=CC=CC=C1	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	B41JRW	Berkchaetoazaphilone A	Investigative	127028674	C25H34O6	430.5	CCCCCCCCCC(=O)[C@H]1[C@@H]2C3=COC(=CC3=CC(=O)[C@@]2(OC1=O)C)C[C@H](C)O	IC50 = 150000 nM	Poor binder
T98269	Caspase-1	B4HP7S	(S)-3-(Benzyloxycarbonylamino)-5-(2-(naphthalen-1-yl)acetamidooxy)-4-oxopentanoic acid	Investigative	49865247	C25H24N2O7	464.5	C1=CC=C(C=C1)COC(=O)N[C@@H](CC(=O)O)C(=O)CONC(=O)CC2=CC=CC3=CC=CC=C32	Ki = 84000 nM	Poor binder
T98269	Caspase-1	B5M8JD	(S)-3-(Benzyloxycarbonylamino)-4-oxo-5-(2-phenylacetamidooxy)pentanoic acid	Investigative	49865195	C21H22N2O7	414.4	C1=CC=C(C=C1)CC(=O)NOCC(=O)[C@H](CC(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 66500 nM	Poor binder
T98269	Caspase-1	B5MZ1X	(S)-3-(Benzyloxycarbonylamino)-4-oxo-5-(5-phenylpentyloxy)pentanoic acid	Investigative	49864837	C24H29NO6	427.5	C1=CC=C(C=C1)CCCCCOCC(=O)[C@H](CC(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 119000 nM	Poor binder
T98269	Caspase-1	B68XRF	Berkchaetorubramine	Investigative	127028996	C27H37NO6	471.6	CCCCCCCCCC(=O)C1=C2C=C3C=C(N(C=C3C(=O)[C@@]2(OC1=O)C)CCO)C[C@H](C)O	IC50 = 50000 nM	Poor binder
T98269	Caspase-1	B6EYA1	(S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11684618	C26H24N2O6S	492.5	COC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CC[C@H]4COC5=CC=CC=C5)C(=O)C2=O	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	B6LN1Y	5-(2-((Methyl(phenyl)amino)methyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	44304162	C20H21N3O4S	399.5	CN(CC1CCCN1S(=O)(=O)C2=CC3=C(C=C2)NC(=O)C3=O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T98269	Caspase-1	B7AQZ3	9-(3,5-Difluorophenyl)-6-(ethylamino)-2-purinecarbonitrile	Investigative	44143091	C14H10F2N6	300.27	CCNC1=C2C(=NC(=N1)C#N)N(C=N2)C3=CC(=CC(=C3)F)F	IC50 = 70794.58 nM	Poor binder
T98269	Caspase-1	B7C5PW	3-Chloro-6-(4-methoxyphenyl)pyridazine-4-carboxamide	Investigative	12085110	C12H10ClN3O2	263.68	COC1=CC=C(C=C1)C2=NN=C(C(=C2)C(=O)N)Cl	IC50 = 66000 nM	Poor binder
T98269	Caspase-1	B81CPH	3-Allyloxycarbonylamino-5-(benzyl-phenethyl-amino)-4-oxo-pentanoic acid	Investigative	44279636	C24H28N2O5	424.5	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CN(CCC1=CC=CC=C1)CC2=CC=CC=C2	Ki = 68000 nM	Poor binder
T98269	Caspase-1	B82FSI	(S)-1-(4-Hydroxybenzyl)-5-[1-(2-methoxymethylpyrrolidinyl)-sulfonyl]isatin	Investigative	44417479	C21H22N2O6S	430.5	COC[C@@H]1CCCN1S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC=C(C=C4)O	IC50 ~ 60000 nM	Poor binder
T98269	Caspase-1	B8EN4C	1-(4-Methylthiobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione	Investigative	11670894	C26H25N3O5S2	523.6	CSC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CCC[C@H]4COC5=CN=CC=C5)C(=O)C2=O	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	B8W7CY	(S)-1-(4-(2-(2-(2-Fluoroethoxy)ethoxy)ethoxy)benzyl)-5-(2-(phenoxymethyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	54582484	C32H35FN2O8S	626.7	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC=C(C=C4)OCCOCCOCCF)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	B97HDS	(S)-1-(2-Fluoropyridin-4-yl-methyl)-5-(2-phenoxymethylazetidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11576622	C24H20FN3O5S	481.5	C1CN([C@@H]1COC2=CC=CC=C2)S(=O)(=O)C3=CC4=C(C=C3)N(C(=O)C4=O)CC5=CC(=NC=C5)F	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BA2RI6	(S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11497112	C26H24N2O5S2	508.6	CSC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CC[C@H]4COC5=CC=CC=C5)C(=O)C2=O	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BA31BP	(S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11584106	C25H22FN3O5S	495.5	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC(=NC=C4)F)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BAL82U	3-(Benzyloxycarbonylamino)-4-oxo-5-(2-cyclohexylethylsulfonylamino)pentanoic acid	Investigative	18354287	C21H30N2O7S	454.5	C1CCC(CC1)CCS(=O)(=O)NCC(=O)C(CC(=O)O)NC(=O)OCC2=CC=CC=C2	IC50 = 136000 nM	Poor binder
T98269	Caspase-1	BAML21	(S)-5-(2-((2,4-Difluorophenoxy)methyl)pyrrolidin-1-ylsulfonyl)-1-(4-(2-fluoroethoxy)benzyl)indoline-2,3-dione	Investigative	54582924	C28H25F3N2O6S	574.6	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC=C(C=C4)OCCF)COC5=C(C=C(C=C5)F)F	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BCBT71	Berkedrimane B	Investigative	51723030	C22H33NO6	407.5	CC(C)[C@@H](C(=O)O[C@H]1CCC([C@H]2[C@]1([C@]3(COC(=O)C3=CC2)O)C)(C)C)NC(=O)C	IC50 = 90000 nM	Poor binder
T98269	Caspase-1	BD2A1L	3-Allyloxycarbonylamino-6-[3-(1H-imidazol-2-yl)-naphthalen-2-yl]-4-oxo-hexanoic acid	Investigative	44280008	C23H23N3O5	421.4	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CCC1=CC2=CC=CC=C2C=C1C3=NC=CN3	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	BFH40N	3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic acid	Investigative	44379693	C23H27NO5	397.5	C1=CC=C(C=C1)CCCCCC(=O)C(CC(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 119000 nM	Poor binder
T98269	Caspase-1	BFSV52	3-(Benzyloxycarbonylamino)-4-oxo-5-(indan-1-ylmethylsulfonylamino)pentanoic acid	Investigative	18354265	C23H26N2O7S	474.5	C1CC2=CC=CC=C2C1CS(=O)(=O)NCC(=O)C(CC(=O)O)NC(=O)OCC3=CC=CC=C3	Ki = 65000 nM	Poor binder
T98269	Caspase-1	BFZN97	(S)-5-(2-((2,4-Difluorophenoxy)methyl)azetidin-1-ylsulfonyl)-1-(4-(2-fluoroethoxy)benzyl)indoline-2,3-dione	Investigative	54583924	C27H23F3N2O6S	560.5	C1CN([C@@H]1COC2=C(C=C(C=C2)F)F)S(=O)(=O)C3=CC4=C(C=C3)N(C(=O)C4=O)CC5=CC=C(C=C5)OCCF	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BHL6J5	3-Allyloxycarbonylamino-4-oxo-8-phenyl-octanoic acid	Investigative	44279649	C18H23NO5	333.4	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CCCCC1=CC=CC=C1	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	BI2JZ1	3-(Benzyloxycarbonylamino)-4-oxo-5-(phenethylsulfonylamino)pentanoic acid	Investigative	18354256	C21H24N2O7S	448.5	C1=CC=C(C=C1)CCS(=O)(=O)NCC(=O)C(CC(=O)O)NC(=O)OCC2=CC=CC=C2	IC50 = 73000 nM	Poor binder
T98269	Caspase-1	BI92UF	Berkedrimane A	Investigative	57333875	C22H33NO5	391.5	CC(C)[C@@H](C(=O)O[C@H]1CCC([C@H]2[C@]1([C@H]3COC(=O)C3=CC2)C)(C)C)NC(=O)C	IC50 = 100000 nM	Poor binder
T98269	Caspase-1	BIGW39	3-Chloro-6-phenyl-pyridazine-4-carboxylic acid amide	Investigative	14450230	C11H8ClN3O	233.65	C1=CC=C(C=C1)C2=NN=C(C(=C2)C(=O)N)Cl	IC50 = 57000 nM	Poor binder
T98269	Caspase-1	BIL21Z	(R)-3-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-propionylamino)-5-oxo-pentanoic acid	Investigative	9827540	C24H34N4O8	506.5	C[C@@H](C(=O)N[C@H](CC=O)CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C	IC50 = 142000 nM	Poor binder
T98269	Caspase-1	BJRK25	4-[4-[2-[[(1R)-1-Carboxy-2-oxoethyl]sulfamoyl]phenoxy]phenyl]benzoic acid	Investigative	44326788	C22H17NO8S	455.4	C1=CC=C(C(=C1)OC2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)N[C@H](C=O)C(=O)O	IC50 = 58000 nM	Poor binder
T98269	Caspase-1	BJV86F	(S)-1-(6-Fluoropyridin-3-ylmethyl)-5-(2-phenoxymethylazetidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11619968	C24H20FN3O5S	481.5	C1CN([C@@H]1COC2=CC=CC=C2)S(=O)(=O)C3=CC4=C(C=C3)N(C(=O)C4=O)CC5=CN=C(C=C5)F	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BK2O8E	3-Chloro-6-pyridin-4-yl-pyridazine-4-carbonitrile	Investigative	23320791	C10H5ClN4	216.62	C1=CN=CC=C1C2=NN=C(C(=C2)C#N)Cl	IC50 = 110000 nM	Poor binder
T98269	Caspase-1	BK9D7O	(S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11519268	C27H26N2O5S2	522.6	CSC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CCC[C@H]4COC5=CC=CC=C5)C(=O)C2=O	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BL67VF	(S)-3-[(S)-2-((S)-2-{[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionyl]-methyl-amino}-3-methyl-butyrylamino)-propionylamino]-4-oxo-butyric acid	Investigative	44315634	C24H34N4O8	506.5	C[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C	Ki = 50000 nM	Poor binder
T98269	Caspase-1	BL9S8W	3-(Benzyloxycarbonylamino)-4-oxo-5-(benzylsulfonylamino)pentanoic acid	Investigative	17871446	C20H22N2O7S	434.5	C1=CC=C(C=C1)COC(=O)NC(CC(=O)O)C(=O)CNS(=O)(=O)CC2=CC=CC=C2	IC50 = 168000 nM	Poor binder
T98269	Caspase-1	BLT5J6	3-Allyloxycarbonylamino-5-(1,2-diphenyl-ethylamino)-4-oxo-pentanoic acid	Investigative	44279696	C23H26N2O5	410.5	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CNC(CC1=CC=CC=C1)C2=CC=CC=C2	Ki = 70000 nM	Poor binder
T98269	Caspase-1	BN18BY	(S)-3-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-propionylamino)-4-oxo-4-phenyl-butyric acid	Investigative	44324063	C29H36N4O8	568.6	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)C1=CC=CC=C1)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)C	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	BODY43	(S)-3-Allyloxycarbonylamino-4-oxo-5-[(E)-(3-phenyl-acryloyl)oxy]-pentanoic acid	Investigative	44279666	C18H19NO7	361.3	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)/C=C/C1=CC=CC=C1	Ki = 90000 nM	Poor binder
T98269	Caspase-1	BOQ4G0	Acetic acid (S)-4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydroindol-1-yl-methyl]phenyl ester	Investigative	11512139	C28H26N2O7S	534.6	CC(=O)OC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CCC[C@H]4COC5=CC=CC=C5)C(=O)C2=O	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BOSA52	3-Allyloxycarbonylamino-4-oxo-5-(3-phenyl-propylamino)-pentanoic acid	Investigative	44279609	C18H24N2O5	348.4	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)CNCCCC1=CC=CC=C1	Ki = 67000 nM	Poor binder
T98269	Caspase-1	BPN5L1	(S)-3-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-propionylamino)-4-cyclohexyl-4-oxo-butyric acid	Investigative	44324147	C29H42N4O8	574.7	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)C1CCCCC1)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)C	Ki ~ 100000 nM	Poor binder
T98269	Caspase-1	BQG78U	3-Allyloxycarbonylamino-5-benzylcarbamoyloxy-4-oxo-pentanoic acid	Investigative	44279661	C17H20N2O7	364.3	C=CCOC(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)NCC1=CC=CC=C1	Ki = 74000 nM	Poor binder
T98269	Caspase-1	BR71UQ	(S)-3-(Benzyloxycarbonylamino)-4-oxo-5-(2-oxopyrrolidin-1-yloxy)pentanoic acid	Investigative	49865138	C17H20N2O7	364.3	C1CC(=O)N(C1)OCC(=O)[C@H](CC(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 87200 nM	Poor binder
T98269	Caspase-1	BS5A8Q	(S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11634649	C25H22FN3O5S	495.5	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=NC(=CC=C4)F)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BT7RG0	(3R)-3-[[(2S)-2-[[(2S)-3-Methyl-2-(naphthalene-2-carbonylamino)butanoyl]amino]propanoyl]amino]-6-phenylhexanoic acid	Investigative	45379836	C31H37N3O5	531.6	C[C@@H](C(=O)N[C@H](CCCC1=CC=CC=C1)CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C2=CC3=CC=CC=C3C=C2	Ki ~ 50000 nM	Poor binder
T98269	Caspase-1	BTU01I	(S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione	Investigative	11576852	C26H23FN2O5S	494.5	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC=C(C=C4)F)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BUM87T	(S)-1-(4-(2-Fluoroethoxy)benzyl)-5-(2-(phenoxymethyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	11533935	C28H27FN2O6S	538.6	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC4=CC=C(C=C4)OCCF)COC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	BV41QN	3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-propionylamino)-propionic acid	Investigative	44316084	C22H32N4O7	464.5	C[C@@H](C(=O)NCCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C	IC50 = 200000 nM	Poor binder
T98269	Caspase-1	BW17HR	(S)-1-(4-(2-(2-Fluoroethoxy)ethoxy)benzyl)-5-(2-(phenoxymethyl)azetidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	54580470	C29H29FN2O7S	568.6	C1CN([C@@H]1COC2=CC=CC=C2)S(=O)(=O)C3=CC4=C(C=C3)N(C(=O)C4=O)CC5=CC=C(C=C5)OCCOCCF	IC50 ~ 50000 nM	Poor binder
T98269	Caspase-1	D0L9AX	Ac-DEVD-CHO	Investigative	644345	C20H30N4O11	502.5	CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)C	IC50 = 70000 nM	Poor binder