TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T96299 Wnt 3a protein B2H6PJ 2-[(Thiophen-2-ylmethylamino)methyl]-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one Investigative 136219323 C13H15N3O2S 277.34 C1COCC2=C1N=C(NC2=O)CNCC3=CC=CS3 IC50 ~ 50000 nM Poor binder T96299 Wnt 3a protein BCI67M N-Ethyl-N-[(4-oxo-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenylpropanamide Investigative 136232694 C19H23N3O3 341.4 CCN(CC1=NC2=C(COCC2)C(=O)N1)C(=O)CCC3=CC=CC=C3 IC50 ~ 50000 nM Poor binder T96299 Wnt 3a protein BR4A2W N-[(4-Oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenylpropanamide Investigative 136244160 C17H19N3O3 313.35 C1COCC2=C1N=C(NC2=O)CNC(=O)CCC3=CC=CC=C3 IC50 ~ 50000 nM Poor binder