TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95913	PI3-kinase gamma	D0E6XR	Dasatinib	Approved	3062316	C22H26ClN7O2S	488	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	D0W5HK	Sorafenib	Approved	216239	C21H16ClF3N4O3	464.8	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	D01RYO	Gefitinib	Patented	123631	C22H24ClFN4O3	446.9	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B05ZXD	8-Ethyl-11-(4-methoxyphenyl)-13-morpholin-4-yl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180794	C22H27N5O2S	425.5	CCN1C2=NC(=NC(=C2C3CCCN3C1=S)N4CCOCC4)C5=CC=C(C=C5)OC	IC50 = 125800 nM	Poor binder
T95913	PI3-kinase gamma	B0G2HM	2-((4-Fluoro-2-methylphenylamino)methyl)-6-morpholinoisonicotinaldehyde	Investigative	44592217	C18H20FN3O2	329.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C=O)N3CCOCC3	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B0P6IU	(R)-2-(3-Benzylmorpholino)-5,5-dimethyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578074	C20H24N2O2S	356.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@H]3CC4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B0R9BU	6-Methyl-8-(2-methylphenoxy)-2-morpholin-4-yl-1H-quinolin-4-one	Investigative	90665816	C21H22N2O3	350.4	CC1=CC=CC=C1OC2=CC(=CC3=C2NC(=CC3=O)N4CCOCC4)C	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B1X9QV	2-[(4-Fluoro-2-methylphenoxy)methyl]-N-(2-hydroxyethyl)-6-morpholin-4-ylpyridine-4-carboxamide	Investigative	44592136	C20H24FN3O4	389.4	CC1=C(C=CC(=C1)F)OCC2=NC(=CC(=C2)C(=O)NCCO)N3CCOCC3	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B21LTA	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(3-hydroxypyrrolidin-1-yl)isonicotinic acid	Investigative	44592259	C18H20FN3O3	345.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N3CCC(C3)O	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B24XLR	2-Morpholinoisonicotinic acid	Investigative	2762479	C10H12N2O3	208.21	C1COCCN1C2=NC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B2AW0M	7-Methyl-9-[(2-methylphenyl)methylamino]-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one	Investigative	11428504	C21H24N4O2	364.4	CC1=CC=CC=C1CNC2=CC(=CN3C2=NC(=CC3=O)N4CCOCC4)C	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B2BMA6	1-Isopropyl-3-(pyrido[3,2-b]pyrazin-7-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905225	C15H14N8	306.33	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=NC=CN=C4N=C3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B2O3PM	10-(4-Methoxyphenyl)-2-morpholin-4-ylbenzo[g]chromen-4-one	Investigative	134143151	C24H21NO4	387.4	COC1=CC=C(C=C1)C2=C3C(=CC4=CC=CC=C42)C(=O)C=C(O3)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B2OF9R	3-(4-Nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905261	C11H8N6O2	256.22	C1=CC(=CC=C1C2=C3C(=NC=NC3=NN2)N)[N+](=O)[O-]	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B2S0VM	1-Tert-Butyl-3-Naphthalen-2-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine	Investigative	5059890	C19H19N5	317.4	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=CC=CC=C4C=C3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B36SBQ	2-Morpholin-4-yl-10-phenylbenzo[g]chromen-4-one	Investigative	134147904	C23H19NO3	357.4	C1COCCN1C2=CC(=O)C3=CC4=CC=CC=C4C(=C3O2)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B3PNJ8	(9,10-Dihydroxy-4,4,11c-trimethyl-1,2,3,4a,5,6-hexahydronaphtho[2,1-b][1]benzofuran-8-yl)boronic acid	Investigative	89819869	C19H25BO5	344.2	B(C1=C2C(=CC(=C1O)O)C3=C(O2)CCC4C3(CCCC4(C)C)C)(O)O	IC50 = 85390 nM	Poor binder
T95913	PI3-kinase gamma	B3VMU7	N-Acetyl-N-[5-(4-morpholin-4-ylpyrido[3,2-d]pyrimidin-2-yl)pyrimidin-2-yl]acetamide	Investigative	76324822	C19H19N7O3	393.4	CC(=O)N(C1=NC=C(C=N1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3)C(=O)C	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B3Z6FC	5-(Pyridin-4-yl)benzo[d]thiazol-2-amine	Investigative	51003380	C12H9N3S	227.29	C1=CC2=C(C=C1C3=CC=NC=C3)N=C(S2)N	IC50 = 77000 nM	Poor binder
T95913	PI3-kinase gamma	B40HLK	2,2'-((3-Chlorophenyl)methylene)bis(sulfanediyl)dibenzoic acid	Investigative	252311	C21H15ClO4S2	430.9	C1=CC=C(C(=C1)C(=O)O)SC(C2=CC(=CC=C2)Cl)SC3=CC=CC=C3C(=O)O	IC50 = 187000 nM	Poor binder
T95913	PI3-kinase gamma	B4CWO6	(S)-5,5-Dimethyl-2-(3-phenylmorpholino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578040	C19H22N2O2S	342.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@@H]3C4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B4HX3I	1-Isopropyl-3-(pyrimidin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905171	C12H13N7	255.28	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CN=CN=C3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B57MKH	N-[5-[3-(2-Hydroxyethylsulfamoyl)-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide	Investigative	127031333	C18H25N3O5S2	427.5	CC1=C(SC(=N1)NC(=O)C(C)(C)C)C2=CC(=C(C=C2)OC)S(=O)(=O)NCCO	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	B57WNT	6-Oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile	Investigative	131989	C11H7N3O	197.19	C1=CN=CC=C1C2=CNC(=O)C(=C2)C#N	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	B58GCW	4-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	42606078	C15H11N3	233.27	C1=CC2=C(NN=C2C=C1)C#CC3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B59FVI	2-(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenol	Investigative	135947977	C11H9N5O	227.22	C1=CC=C(C(=C1)C2=C3C(=NC=NC3=NN2)N)O	IC50 = 50000 nM	Poor binder
T95913	PI3-kinase gamma	B5E8FS	1-Isopropyl-3-(isoquinolin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905215	C17H16N6	304.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)C=NC=C4)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B5X8EO	3-(2-Chloroquinolin-3-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905220	C17H15ClN6	338.8	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=CC=CC=C4N=C3Cl)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B63WDX	1-Methyl-3-(4-phenylmethoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	52942202	C19H17N5O	331.4	CN1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)OCC4=CC=CC=C4)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B6LVO3	N-[6-[4-(Methylsulfamoyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552298	C15H15N5O3S	345.4	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=C(C=C3)S(=O)(=O)NC	IC50 ~ 50118.72 nM	Poor binder
T95913	PI3-kinase gamma	B7D0OZ	1-(Cyclopropylmethyl)-4-[2-[[(1R)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184541	C23H27N3O2S	409.5	C[C@H](C1CCOCC1)NC2=NC3=C(S2)C=C(C=C3)C4=CC(=O)N(C=C4)CC5CC5	IC50 = 63095.73 nM	Poor binder
T95913	PI3-kinase gamma	B7XED2	2-(Pyridin-4-yl)benzo[d]oxazol-5-ol	Investigative	4912089	C12H8N2O2	212.2	C1=CC2=C(C=C1O)N=C(O2)C3=CC=NC=C3	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	B83MYU	Ethyl 2-morpholinoisonicotinate	Investigative	2762944	C12H16N2O3	236.27	CCOC(=O)C1=CC(=NC=C1)N2CCOCC2	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B84BVT	2-(Bis(2-hydroxyethyl)amino)-6-((4-fluoro-2-methylphenylamino)methyl)isonicotinic acid	Investigative	44592262	C18H22FN3O4	363.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N(CCO)CCO	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B89CGE	3-(1-Isopropyl-4-(methylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenol	Investigative	24905257	C15H17N5O	283.33	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=CC=C3)O)NC	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B8AW2L	1-Isopropyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905177	C17H21N5O3	343.4	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C(=C3)OC)OC)OC)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	B8POJ5	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(piperazin-1-yl)isonicotinic acid	Investigative	44592218	C18H21FN4O2	344.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N3CCNCC3	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	B93BWV	5-(Pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine	Investigative	53319932	C12H9N3	195.22	C1=CNC2=NC=C(C=C21)C3=CC=NC=C3	IC50 = 70000 nM	Poor binder
T95913	PI3-kinase gamma	B9BM4O	3-Amino-7-chloro-1,2,4-benzotriazine	Investigative	95001	C7H5ClN4	180.59	C1=CC2=C(C=C1Cl)N=NC(=N2)N	IC50 = 53000 nM	Poor binder
T95913	PI3-kinase gamma	B9QG3A	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	22346757	C17H13N5O	303.32	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=C4C(=NC=NC4=NN3)N	IC50 = 50000 nM	Poor binder
T95913	PI3-kinase gamma	BB1E5A	(R)-5,5-Dimethyl-2-(3-phenylmorpholino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one	Investigative	44578039	C19H22N2O2S	342.5	CC1(CC2=C(C(=O)C1)SC(=N2)N3CCOC[C@H]3C4=CC=CC=C4)C	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BB7SC5	[3-(4-Morpholin-4-ylpyrido[2,3-d]pyrimidin-2-yl)phenyl]methanol	Investigative	76310249	C18H18N4O2	322.4	C1COCCN1C2=NC(=NC3=C2C=CC=N3)C4=CC=CC(=C4)CO	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BBCR35	3-(1,2,3,4-Tetrahydronaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905268	C15H15N5	265.31	C1CC2=CC=CC=C2CC1C3=C4C(=NC=NC4=NN3)N	IC50 = 50000 nM	Poor binder
T95913	PI3-kinase gamma	BBJI17	7-(4-Morpholinyl)pyrimido[4,5-d]pyrimidin-4-amine	Investigative	2816900	C10H12N6O	232.24	C1COCCN1C2=NC=C3C(=NC=NC3=N2)N	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	BBK16J	4-(4-Morpholin-4-ylpyrido[3,2-d]pyrimidin-2-yl)aniline	Investigative	76335669	C17H17N5O	307.35	C1COCCN1C2=NC(=NC3=C2N=CC=C3)C4=CC=C(C=C4)N	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BBV89X	4-[2-(3-Methoxyphenyl)pyrido[3,2-d]pyrimidin-4-yl]morpholine	Investigative	76317467	C18H18N4O2	322.4	COC1=CC=CC(=C1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BBWU45	6-(4-Amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905227	C19H18N6O	346.4	C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)NC(=O)C=C5)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BC23WJ	3-(H-Imidazo[1,2-a]pyridin-7-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905246	C15H15N7	293.33	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=NC=CN4C=C3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BC8PK4	3-Benzyl-5-morpholin-4-ylthieno[3,2-b]pyran-7-one	Investigative	44181492	C18H17NO3S	327.4	C1COCCN1C2=CC(=O)C3=C(O2)C(=CS3)CC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BD0JM9	4-(1H-Pyrazolo[3,4-b]pyridin-4-yl)morpholine	Investigative	53317325	C10H12N4O	204.23	C1COCCN1C2=C3C=NNC3=NC=C2	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	BD4B2E	1-Isopropyl-3-(2,3-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905178	C16H19N5O2	313.35	CC(C)N1C2=NC=NC(=C2C(=N1)C3=C(C(=CC=C3)OC)OC)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BD6AQ8	1-(Cyclopropylmethyl)-4-[2-[[(1S)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184542	C23H27N3O2S	409.5	C[C@@H](C1CCOCC1)NC2=NC3=C(S2)C=C(C=C3)C4=CC(=O)N(C=C4)CC5CC5	IC50 ~ 199526.23 nM	Poor binder
T95913	PI3-kinase gamma	BD8H7U	N-[6-(5-Methylsulfonylpyridin-3-Yl)-[1,2,4]triazolo[1,5-A]pyridin-2-Yl]ethanamide	Investigative	25128663	C14H13N5O3S	331.35	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC(=CN=C3)S(=O)(=O)C	IC50 ~ 63095.73 nM	Poor binder
T95913	PI3-kinase gamma	BDR9I6	1-(Cyclopropylmethyl)-4-[2-[(1,1-dioxothian-4-yl)methylamino]-1,3-benzothiazol-6-yl]pyridin-2-one	Investigative	122184543	C22H25N3O3S2	443.6	C1CC1CN2C=CC(=CC2=O)C3=CC4=C(C=C3)N=C(S4)NCC5CCS(=O)(=O)CC5	IC50 = 50118.72 nM	Poor binder
T95913	PI3-kinase gamma	BENP95	4-(2-Pyridin-3-ylpyrido[3,2-d]pyrimidin-4-yl)morpholine	Investigative	76317468	C16H15N5O	293.32	C1COCCN1C2=NC(=NC3=C2N=CC=C3)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BEO7U0	3-(4-Butoxy-3-methoxyphenyl)pentanedioic acid	Investigative	244740	C16H22O6	310.34	CCCCOC1=C(C=C(C=C1)C(CC(=O)O)CC(=O)O)OC	IC50 = 134000 nM	Poor binder
T95913	PI3-kinase gamma	BF35LM	1-Methyl-3-(3-phenylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	52944356	C18H15N5	301.3	CN1C2=NC=NC(=C2C(=N1)C3=CC=CC(=C3)C4=CC=CC=C4)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BF56ON	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(2-hydroxyethylamino)isonicotinic acid	Investigative	44592261	C16H18FN3O3	319.33	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)NCCO	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BGPS06	N-[7-Methyl-6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552467	C15H15N5O3S	345.4	CC1=CC2=NC(=NN2C=C1C3=CC(=CN=C3)S(=O)(=O)C)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BGUK37	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(piperidin-1-yl)isonicotinic acid	Investigative	44592219	C19H22FN3O2	343.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N3CCCCC3	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BH5YK7	8-[(2R)-1-(3,5-Difluorophenyl)pyrrolidin-2-yl]-6-(morpholine-4-carbonyl)-2-morpholino-chromen-4-one	Investigative	66557964	C28H29F2N3O5	525.5	C1C[C@@H](N(C1)C2=CC(=CC(=C2)F)F)C3=CC(=CC4=C3OC(=CC4=O)N5CCOCC5)C(=O)N6CCOCC6	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BH8LE3	2-Pyridin-4-yl-benzooxazol-5-ylamine	Investigative	736009	C12H9N3O	211.22	C1=CC2=C(C=C1N)N=C(O2)C3=CC=NC=C3	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	BHAX60	2-((4-Fluoro-2-methylphenylamino)methyl)-6-((2-hydroxyethyl)(methyl)amino)isonicotinic acid	Investigative	44592260	C17H20FN3O3	333.36	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N(C)CCO	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BHMW36	5-(Pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine	Investigative	53318614	C10H8N6	212.21	C1=CN=CC=C1C2=NC3=NC(=NN3C=C2)N	IC50 = 55400 nM	Poor binder
T95913	PI3-kinase gamma	BJ39AZ	2-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenylamino)propan-1-ol	Investigative	24905198	C18H24N6O2	356.4	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC(=C(C=C3)NC(C)CO)OC)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BJF52U	3-(4-Thiomorpholin-4-ylpyrido[3,2-d]pyrimidin-2-yl)phenol	Investigative	76335666	C17H16N4OS	324.4	C1CSCCN1C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BJT7O1	2-Chloro-6-((4-fluoro-2-methylphenylamino)methyl)isonicotinic acid	Investigative	44592338	C14H12ClFN2O2	294.71	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BK0MV6	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(4-hydroxyphenyl)isonicotinic acid	Investigative	135986100	C20H17FN2O3	352.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)C3=CC=C(C=C3)O	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BK7VL4	7-(Morpholin-4-yl)quinazolin-4(3H)-one	Investigative	135742360	C12H13N3O2	231.25	C1COCCN1C2=CC3=C(C=C2)C(=O)NC=N3	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	BL2D5C	4-Methyl-2-morpholin-4-yl-thiazole-5-carboxylic acid	Investigative	6484194	C9H12N2O3S	228.27	CC1=C(SC(=N1)N2CCOCC2)C(=O)O	IC50 ~ 83300 nM	Poor binder
T95913	PI3-kinase gamma	BL45FR	N-(2-Hydroxyethyl)-N-methyl-2-morpholin-4-yl-4-oxo-9-[(1R)-1-phenoxyethyl]pyrido[1,2-a]pyrimidine-7-carboxamide	Investigative	118709092	C24H28N4O5	452.5	C[C@H](C1=CC(=CN2C1=NC(=CC2=O)N3CCOCC3)C(=O)N(C)CCO)OC4=CC=CC=C4	IC50 = 83000 nM	Poor binder
T95913	PI3-kinase gamma	BLCX82	(2-((4-Fluoro-2-methylphenylamino)methyl)-6-morpholinopyridin-4-yl)methanol	Investigative	44592216	C18H22FN3O2	331.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)CO)N3CCOCC3	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BLY40Q	3-[4-(4,4-Difluoropiperidin-1-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76335667	C18H16F2N4O	342.3	C1CN(CCC1(F)F)C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BM24CI	3-(3-(2,6-Dichlorobenzyloxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905265	C18H13Cl2N5O	386.2	C1=CC(=CC(=C1)OCC2=C(C=CC=C2Cl)Cl)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BM76KW	8-Methyl-7-[2-(4-methylpiperazin-1-yl)ethoxy]-2-morpholin-4-yl-1,3-benzoxazin-4-one	Investigative	17756679	C20H28N4O4	388.5	CC1=C(C=CC2=C1OC(=NC2=O)N3CCOCC3)OCCN4CCN(CC4)C	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BN2F1K	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(pyrrolidin-1-yl)isonicotinic acid	Investigative	44592258	C18H20FN3O2	329.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)N3CCCC3	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BND96I	8-Ethyl-11-(3-methoxyphenyl)-13-morpholin-4-yl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180793	C22H27N5O2S	425.5	CCN1C2=NC(=NC(=C2C3CCCN3C1=S)N4CCOCC4)C5=CC(=CC=C5)OC	IC50 = 91560 nM	Poor binder
T95913	PI3-kinase gamma	BNI1D2	6-[2-Hydroxyethyl(naphthalen-1-ylmethyl)amino]-4-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one	Investigative	70675846	C22H26N4O3	394.5	C[C@H]1CN(CCO1)C2=NC(=O)NC(=C2)N(CCO)CC3=CC=CC4=CC=CC=C43	IC50 = 97400 nM	Poor binder
T95913	PI3-kinase gamma	BNX13Z	6-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)quinolin-2(1H)-one	Investigative	24905226	C17H16N6O	320.3	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)NC(=O)C=C4)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BOE0I8	3-Morpholin-4-yl-2-(7H-purin-6-ylsulfanylmethyl)quinazolin-4-one	Investigative	10204538	C18H17N7O2S	395.4	C1COCCN1N2C(=NC3=CC=CC=C3C2=O)CSC4=NC=NC5=C4NC=N5	IC50 = 137900 nM	Poor binder
T95913	PI3-kinase gamma	BOH29Z	2-((4-Fluoro-2-methylphenylamino)methyl)-N-(2-hydroxyethyl)-6-(2-hydroxyethylamino)isonicotinamide	Investigative	44592339	C18H23FN4O3	362.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)NCCO)NCCO	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BOM52F	6-[6-(Methylaminomethyl)pyridin-3-yl]-1,3-benzothiazol-2-amine	Investigative	122184468	C14H14N4S	270.35	CNCC1=NC=C(C=C1)C2=CC3=C(C=C2)N=C(S3)N	IC50 = 50118.72 nM	Poor binder
T95913	PI3-kinase gamma	BOM84S	6-(Benzyloxy)-5-methoxy-1H-indole-2-carboxylic acid	Investigative	260801	C17H15NO4	297.3	COC1=C(C=C2C(=C1)C=C(N2)C(=O)O)OCC3=CC=CC=C3	IC50 = 105000 nM	Poor binder
T95913	PI3-kinase gamma	BPZA98	4-[2-(4-Methoxyphenyl)pyrido[3,2-d]pyrimidin-4-yl]morpholine	Investigative	76313939	C18H18N4O2	322.4	COC1=CC=C(C=C1)C2=NC3=C(C(=N2)N4CCOCC4)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BR0Y9C	3-[4-(4-Methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76310247	C18H19N5O	321.4	CN1CCN(CC1)C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BR4XO3	N-[6-[3-(Benzylsulfamoyl)-4-methoxyphenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552346	C22H21N5O4S	451.5	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC(=C(C=C3)OC)S(=O)(=O)NCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BT6N0R	3-(3-Phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905262	C17H13N5O	303.32	C1=CC=C(C=C1)OC2=CC=CC(=C2)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BT7B6U	3-[4-(1,1-Dioxo-1,4-thiazinan-4-yl)pyrido[3,2-d]pyrimidin-2-yl]phenol	Investigative	76317466	C17H16N4O3S	356.4	C1CS(=O)(=O)CCN1C2=NC(=NC3=C2N=CC=C3)C4=CC(=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BT85EO	6-Bromoimidazo[1,2-a]pyridin-2-amine	Investigative	44119296	C7H6BrN3	212.05	C1=CC2=NC(=CN2C=C1Br)N	IC50 = 156000 nM	Poor binder
T95913	PI3-kinase gamma	BUYJ59	6-((4-Fluoro-2-methylphenylamino)methyl)-2,3''-bipyridine-4-carboxylic acid	Investigative	44592300	C19H16FN3O2	337.3	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BV36FK	5-Morpholin-4-ylthieno[3,2-b]pyran-7-one	Investigative	44181603	C11H11NO3S	237.28	C1COCCN1C2=CC(=O)C3=C(O2)C=CS3	IC50 ~ 50000 nM	Poor binder
T95913	PI3-kinase gamma	BV6S9M	(S)-2-Amino-1-(4-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)piperazin-1-yl)-3-phenylpropan-1-one	Investigative	71526878	C28H31F2N9O2	563.6	C1CN(CCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5)C(=O)[C@H](CC6=CC=CC=C6)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BW34XQ	N-[6-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide	Investigative	66552297	C15H14N4O3S	330.4	CC(=O)NC1=NN2C=C(C=CC2=N1)C3=CC=C(C=C3)S(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BWN2Z4	(2-((4-Fluoro-2-methylphenylamino)methyl)-6-(3-hydroxypyrrolidin-1-yl)pyridin-4-yl)(3-hydroxypyrrolidin-1-yl)methanone	Investigative	44592340	C22H27FN4O3	414.5	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)N3CCC(C3)O)N4CCC(C4)O	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BWQN23	3-((1H-Indazol-3-yl)ethynyl)aniline	Investigative	42606076	C15H11N3	233.27	C1=CC2=C(NN=C2C=C1)C#CC3=CC(=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BWS24D	3-(4-Biphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	24905267	C17H13N5	287.32	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=C4C(=NC=NC4=NN3)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BX5CQ8	6-(5-Methylsulfonylpyridin-3-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine	Investigative	66552468	C13H10F3N5O2S	357.31	CS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BX72GB	3-[2-Amino-7-(3-hydroxyphenyl)-4-{[3-(morpholin-4-yl)propyl]amino}pteridin-6-yl]phenol	Investigative	17755611	C25H27N7O3	473.5	C1COCCN1CCCNC2=NC(=NC3=C2N=C(C(=N3)C4=CC(=CC=C4)O)C5=CC(=CC=C5)O)N	IC50 = 51000 nM	Poor binder
T95913	PI3-kinase gamma	BXW73J	5-(4-Amino-1-((4-phenyloxazol-5-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenol	Investigative	24905308	C21H15FN6O2	402.4	C1=CC=C(C=C1)C2=C(OC=N2)CN3C4=NC=NC(=C4C(=N3)C5=CC(=C(C=C5)F)O)N	IC50 = 100000 nM	Poor binder
T95913	PI3-kinase gamma	BY95HQ	2-((4-Fluoro-2-methylphenylamino)methyl)-6-(2-hydroxyphenyl)isonicotinic acid	Investigative	135986101	C20H17FN2O3	352.4	CC1=C(C=CC(=C1)F)NCC2=NC(=CC(=C2)C(=O)O)C3=CC=CC=C3O	IC50 ~ 100000 nM	Poor binder
T95913	PI3-kinase gamma	BZ58CK	3-(2-Chlorophenyl)-7-fluoro-2-(7H-purin-6-ylsulfanylmethyl)quinazolin-4-one	Investigative	10181657	C20H12ClFN6OS	438.9	C1=CC=C(C(=C1)N2C(=NC3=C(C2=O)C=CC(=C3)F)CSC4=NC=NC5=C4NC=N5)Cl	IC50 = 145200 nM	Poor binder
T95913	PI3-kinase gamma	D00ZIK	IC87114	Investigative	9908783	C22H19N7O	397.4	CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C(N=CN=C54)N	IC50 = 61000 nM	Poor binder
T95913	PI3-kinase gamma	D03QQH	AMA37	Investigative	16760391	C17H17NO3	283.32	C1COCCN1C2=CC(=C(C=C2)C(=O)C3=CC=CC=C3)O	IC50 = 100000 nM	Poor binder