TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T94627 Solute carrier family 28 member 2 B19UZC 5'-o-Acetyladenosine Investigative 11953391 C12H15N5O5 309.28 CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B1DZU9 (2R,3R,4S,5R)-2-[6-Amino-8-[(2-methylphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Investigative 118737953 C18H22N6O4 386.4 CC1=CC=CC=C1CNC2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N IC50 = 65000 nM Poor binder T94627 Solute carrier family 28 member 2 B2D5BV [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl ethyl carbonate Investigative 22803321 C13H17N5O6 339.3 CCOC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B2XI4P Adenosine-derived inhibitor, 6 Investigative 13965968 C17H20N6O4 372.4 C1=CC=C(C=C1)CNC2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N IC50 = 52000 nM Poor binder T94627 Solute carrier family 28 member 2 B3XZA8 [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hexanoate Investigative 118737964 C16H23N5O5 365.38 CCCCCC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B46CVH [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-benzylcarbamate Investigative 118737970 C18H20N6O5 400.4 C1=CC=C(C=C1)CNC(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B4I3BY [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 2-phenylacetate Investigative 118737965 C18H19N5O5 385.4 C1=CC=C(C=C1)CC(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B4T7FD (2R,3R,4S,5R)-2-[6-Amino-8-[(2-methoxyphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Investigative 118737959 C18H22N6O5 402.4 COC1=CC=CC=C1CNC2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B6KBW9 [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-pentylcarbamate Investigative 118737969 C16H24N6O5 380.4 CCCCCNC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 B74ZSC [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-methylcarbamate Investigative 56975630 C12H16N6O5 324.29 CNC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BEP49S [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl methyl carbonate Investigative 118737966 C12H15N5O6 325.28 COC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BGD26U [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl benzyl carbonate Investigative 118737968 C18H19N5O6 401.4 C1=CC=C(C=C1)COC(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BL6HE1 Propionyl adenylate Investigative 11544329 C13H17N5O5 323.3 CCC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BR25AM (2R,3R,4S,5R)-2-[6-Amino-8-[(2-phenylphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Investigative 118737962 C23H24N6O4 448.5 C1=CC=C(C=C1)C2=CC=CC=C2CNC3=NC4=C(N=CN=C4N3[C@H]5[C@@H]([C@@H]([C@H](O5)CO)O)O)N IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BU4I9J [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl pentyl carbonate Investigative 118737967 C16H23N5O6 381.38 CCCCCOC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 BYMX06 [(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-ethylcarbamate Investigative 46887269 C13H18N6O5 338.32 CCNC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O IC50 ~ 100000 nM Poor binder T94627 Solute carrier family 28 member 2 D06WAL Phlorizin Investigative 6072 C21H24O10 436.4 C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O IC50 = 100000 nM Poor binder