TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T94621	RAC-beta serine/threonine-protein kinase	B0M4XA	4-Phenyl-1H-pyrazole	Investigative	139106	C9H8N2	144.17	C1=CC=C(C=C1)C2=CNN=C2	IC50 = 135000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B2BO0H	6-(4-{[4-(1H-1,3-Benzodiazol-2-yl)piperidin-1-yl]methyl}phenyl)-5-phenylpyridine-3-carbonitrile	Investigative	11454186	C31H27N5	469.6	C1CN(CCC1C2=NC3=CC=CC=C3N2)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B3X0ZT	7-Azaindole	Investigative	9222	C7H6N2	118.14	C1=CC2=C(NC=C2)N=C1	IC50 ~ 100000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B4CH0F	1-(1-{[4-(3-Phenylquinoxalin-2-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	9871034	C33H29N5O	511.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC=CC=C6N=C5C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B4E3WB	6-(4-{[4-(6-Methyl-1H-1,3-benzodiazol-2-yl)piperidin-1-yl]methyl}phenyl)-5-phenylpyridine-3-carbonitrile	Investigative	11225451	C32H29N5	483.6	CC1=CC2=C(C=C1)N=C(N2)C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B4M5KP	({4-[3-Phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)({[4-(1,2,3-thiadiazol-4-yl)phenyl]methyl})amine	Investigative	11454871	C28H22N8S	502.6	C1=CC=C(C=C1)C2=C(N=CC(=C2)C3=NNN=N3)C4=CC=C(C=C4)CNCC5=CC=C(C=C5)C6=CSN=N6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B5ON0T	6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789254	C14H20N6	272.35	C1CCNC2(C1)CCN(CC2)C3=NC=NC4=C3NC=N4	IC50 = 66000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B7T4PX	2-[1-({4-[3-Phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H-1,3-benzodiazole	Investigative	11409661	C31H28N8	512.6	C1CN(CCC1C2=NC3=CC=CC=C3N2)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B8B5JS	1-(1-{[4-(2-Phenylquinolin-3-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	23647020	C34H30N4O	510.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=CC6=CC=CC=C6N=C5C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B8CK1B	6-Fluoro-2-[1-({4-[3-phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H-1,3-benzodiazole	Investigative	11341558	C31H27FN8	530.6	C1CN(CCC1C2=NC3=C(N2)C=C(C=C3)F)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	B9CSY0	1-(1-{[4-(6-Oxo-3-phenyl-1,6-dihydropyrazin-2-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	10174144	C29H27N5O2	477.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=CC(=O)N5)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BA18MN	6-(4-{[4-(2-Oxo-2,3-Dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]methyl}phenyl)-5-phenylnicotinonitrile	Investigative	9957031	C31H27N5O	485.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BCH32R	1-(8-Methyl-7H-purin-6-yl)piperidin-4-amine	Investigative	24828715	C11H16N6	232.29	CC1=NC2=C(N1)C(=NC=N2)N3CCC(CC3)N	IC50 = 110000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BCP5W4	6-(Piperidin-1-yl)-9H-purine	Investigative	3129049	C10H13N5	203.24	C1CCN(CC1)C2=NC=NC3=C2NC=N3	IC50 = 59000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BE0IB7	1-[1-({4-[3-Phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H-1,3-benzodiazole	Investigative	11364261	C31H28N8	512.6	C1CN(CCC1N2C=NC3=CC=CC=C32)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BE5HV2	6-(4-{[4-(2-Methyl-1H-1,3-benzodiazol-1-yl)piperidin-1-yl]methyl}phenyl)-5-phenylpyridine-3-carbonitrile	Investigative	11260243	C32H29N5	483.6	CC1=NC2=CC=CC=C2N1C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BG57FI	2-Methyl-1-[1-({4-[3-phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H-1,3-benzodiazole	Investigative	11180030	C32H30N8	526.6	CC1=NC2=CC=CC=C2N1C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BJ4Y6E	5-Phenyl-6-[4-[[[4-(thiadiazol-4-yl)phenyl]methylamino]methyl]phenyl]pyridine-3-carbonitrile	Investigative	9912061	C28H21N5S	459.6	C1=CC=C(C=C1)C2=C(N=CC(=C2)C#N)C3=CC=C(C=C3)CNCC4=CC=C(C=C4)C5=CSN=N5	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BJXN94	6-(4-{[4-(6-Fluoro-1H-benzimidazol-2-yl)piperidin-1-yl]methyl}phenyl)-5-phenylnicotinonitrile	Investigative	11431759	C31H26FN5	487.6	C1CN(CCC1C2=NC3=C(N2)C=C(C=C3)F)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BL8VQ3	3,5-Dimethyl-4-phenyl-1H-pyrazole	Investigative	2753118	C11H12N2	172.23	CC1=C(C(=NN1)C)C2=CC=CC=C2	IC50 = 72000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BM2CH5	N-[[4-[2-(2-Aminopyridin-3-yl)-6-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide	Investigative	58345169	C31H24N6O	496.6	C1=CC=C(C=C1)C2=CC3=C(N=C2)N(C(=N3)C4=C(N=CC=C4)N)C5=CC=C(C=C5)CNC(=O)C6=CC=CC=C6	IC50 = 51000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BNA26F	(3S,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71720141	C18H19N3O	293.4	CN1C[C@@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BP65OT	1-(1-{[4-(6-Benzyl-5-oxo-3-phenyl-4,5-dihydropyrazin-2-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	23647016	C36H33N5O2	567.7	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(NC(=O)C(=N5)CC6=CC=CC=C6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BQ5LG8	(3R,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71718330	C18H19N3O	293.4	CN1C[C@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BTB2X5	1-[1-({4-[6-(Butan-2-yl)-5-oxo-3-phenyl-4,5-dihydropyrazin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	10128689	C33H35N5O2	533.7	CCC(C)C1=NC(=C(NC1=O)C2=CC=CC=C2)C3=CC=C(C=C3)CN4CCC(CC4)N5C6=CC=CC=C6NC5=O	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BVBC23	3-Methyl-4-phenyl-1H-pyrazole	Investigative	139601	C10H10N2	158.2	CC1=C(C=NN1)C2=CC=CC=C2	IC50 = 80000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BW51IJ	1-(1-{[4-(3-Phenylquinolin-2-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	21103107	C34H30N4O	510.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC=CC=C6C=C5C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BW98OF	6-(4-{[4-(1H-1,3-Benzodiazol-1-yl)piperidin-1-yl]methyl}phenyl)-5-phenylpyridine-3-carbonitrile	Investigative	11374804	C31H27N5	469.6	C1CN(CCC1N2C=NC3=CC=CC=C32)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C#N)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BWHL87	6-Methyl-2-[1-({4-[3-phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-1H-1,3-benzodiazole	Investigative	11168481	C32H30N8	526.6	CC1=CC2=C(C=C1)N=C(N2)C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T94621	RAC-beta serine/threonine-protein kinase	BXH1T2	1-[1-({4-[3-Phenyl-5-(1H-1,2,3,4-tetrazol-5-yl)pyridin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	11272514	C31H28N8O	528.6	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(C=C(C=N5)C6=NNN=N6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder