TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T93266 Hyperpolarization cyclic nucleotide-gated channel 1 B4GO9S 2-Ethoxy-N-[[1-(4-phenylpiperazin-1-yl)cyclohexyl]methyl]benzamide Investigative 56672421 C26H35N3O2 421.6 CCOC1=CC=CC=C1C(=O)NCC2(CCCCC2)N3CCN(CC3)C4=CC=CC=C4 IC50 ~ 199526.23 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 B4VJ8P 3-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide Investigative 56672532 C23H29N3O2 379.5 CN1CCN(CC1)C2(CC3=CC=CC=C3C2)CNC(=O)C4=CC(=CC=C4)OC IC50 = 63095.73 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 B5DQ6U 4-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide Investigative 56679227 C23H29N3O2 379.5 CN1CCN(CC1)C2(CC3=CC=CC=C3C2)CNC(=O)C4=CC=C(C=C4)OC IC50 = 100000 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BBVU25 2-Ethyl-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamide Investigative 56682419 C23H37N3O 371.6 CCC1=CC=CC=C1C(=O)NCC2(CCCCC2)N3CCN(CC3)C(C)C IC50 ~ 199526.23 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BBZ52A 2-Chloro-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamide Investigative 39734391 C19H28ClN3O 349.9 CN1CCN(CC1)C2(CCCCC2)CNC(=O)C3=CC=CC=C3Cl IC50 ~ 199526.23 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BDEY35 2-Hydroxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide Investigative 56675914 C22H27N3O2 365.5 CN1CCN(CC1)C2(CC3=CC=CC=C3C2)CNC(=O)C4=CC=CC=C4O IC50 ~ 199526.23 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BEVG30 2-Methoxy-N-[(2-piperidin-1-yl-1,3-dihydroinden-2-yl)methyl]benzamide Investigative 56658685 C23H28N2O2 364.5 COC1=CC=CC=C1C(=O)NCC2(CC3=CC=CC=C3C2)N4CCCCC4 IC50 = 50118.72 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BT3S2J 2-Methoxy-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide Investigative 17616875 C15H23N3O2 277.36 CN1CCN(CC1)CCNC(=O)C2=CC=CC=C2OC IC50 ~ 199526.23 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BX3SJ8 2-Methyl-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamide Investigative 56665614 C20H31N3O 329.5 CC1=CC=CC=C1C(=O)NCC2(CCCCC2)N3CCN(CC3)C IC50 = 63095.73 nM Poor binder T93266 Hyperpolarization cyclic nucleotide-gated channel 1 BZV4C5 2-Methoxy-N-[(1-morpholin-4-ylcyclohexyl)methyl]benzamide Investigative 16015637 C19H28N2O3 332.4 COC1=CC=CC=C1C(=O)NCC2(CCCCC2)N3CCOCC3 IC50 ~ 199526.23 nM Poor binder