TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92687	Gastric H(+)/K(+) ATPase	D02DPA	Cimetidine	Approved	2756	C10H16N6S	252.34	CC1=C(N=CN1)CSCCNC(=NC)NC#N	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B1AI9G	2-(1H-Benzoimidazole-2-sulfinylmethyl)-4-chloro-phenylamine	Investigative	14064689	C14H12ClN3OS	305.8	C1=CC=C2C(=C1)NC(=N2)S(=O)CC3=C(C=CC(=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B1X9NL	2,2-Difluoro-6-[(4,5-dimethoxy-2-pyridinyl)methylsulfinyl]-5H-1,3-dioxolo[4,5-f]benzimidazole	Investigative	15163510	C16H13F2N3O5S	397.4	COC1=C(C=NC(=C1)CS(=O)C2=NC3=CC4=C(C=C3N2)OC(O4)(F)F)OC	IC50 = 63095.73 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B21HNV	6-Methoxy-3,4-dimethyl-1-o-tolyl-1H-pyrrolo[3,2-c]quinoline	Investigative	9796998	C21H20N2O	316.4	CC1=CC=CC=C1N2C=C(C3=C(N=C4C(=C32)C=CC=C4OC)C)C	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B25QVF	Ethyl 4-amino-3-[[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]benzoate	Investigative	14064698	C18H19N3O4S	373.4	CCOC(=O)C1=CC(=C(C=C1)N)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B3QZ4H	2-[(E)-2-(4-Methoxy-3,5-dimethyl-pyridin-2-yl)-vinyl]-2-methyl-2,3-dihydro-benzothiazole	Investigative	44299614	C18H20N2OS	312.4	CC1=CN=C(C(=C1OC)C)/C=C/C2(NC3=CC=CC=C3S2)C	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B3R9IY	N-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-guanidine	Investigative	7176110	C11H12N4OS	248.31	COC1=CC=CC(=C1)C2=CSC(=N2)N=C(N)N	IC50 = 60000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B4X5ZS	2-(1H-Benzoimidazole-2-sulfinylmethyl)-4-chloro-6-methyl-phenylamine	Investigative	14064701	C15H14ClN3OS	319.8	CC1=CC(=CC(=C1N)CS(=O)C2=NC3=CC=CC=C3N2)Cl	IC50 = 60000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B4YD0Z	(6-Methoxy-1-o-tolyl-1H-pyrrolo[3,2-c]quinolin-3-yl)-methanol	Investigative	44327587	C20H18N2O2	318.4	CC1=CC=CC=C1N2C=C(C3=CN=C4C(=C32)C=CC=C4OC)CO	IC50 = 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B5POB6	2-(1H-Benzoimidazole-2-sulfinylmethyl)-4-trifluoromethyl-phenylamine	Investigative	14064692	C15H12F3N3OS	339.3	C1=CC=C2C(=C1)NC(=N2)S(=O)CC3=C(C=CC(=C3)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B8HQ4L	1-(2-Methyl-4-fluorophenyl)-6-methoxy-1H-pyrrolo[3,2-c]quinoline-3-methanol	Investigative	44327862	C20H17FN2O2	336.4	CC1=C(C=CC(=C1)F)N2C=C(C3=CN=C4C(=C32)C=CC=C4OC)CO	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	B9OJ8L	2-[4-(3-Chlorophenyl)-1,3-thiazol-2-yl]guanidine;hydrobromide	Investigative	24854877	C10H10BrClN4S	333.64	C1=CC(=CC(=C1)Cl)C2=CSC(=N2)N=C(N)N.Br	IC50 = 53000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BA8SW0	N-[2-(1H-Benzoimidazole-2-sulfinylmethyl)-phenyl]-acetamide	Investigative	14064683	C16H15N3O2S	313.4	CC(=O)NC1=CC=CC=C1CS(=O)C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BBS2R7	Timoprazole	Investigative	72171	C13H11N3OS	257.31	C1=CC=C2C(=C1)NC(=N2)S(=O)CC3=CC=CC=N3	IC50 = 130000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BCT7G3	5-Chloro-2-[2-(4-methoxy-3,5-dimethyl-pyridin-2-yl)-ethyl]-2-methyl-2,3-dihydro-benzothiazole	Investigative	44299550	C18H21ClN2OS	348.9	CC1=CN=C(C(=C1OC)C)CCC2(NC3=C(S2)C=CC(=C3)Cl)C	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BI91ZA	1-(2-Methylphenyl)-6-methoxy-1H-pyrrolo[3,2-c]quinoline-3-ethanol	Investigative	44327865	C21H20N2O2	332.4	CC1=CC=CC=C1N2C=C(C3=CN=C4C(=C32)C=CC=C4OC)CCO	IC50 = 80000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BJ4R2F	1-(2-Methyl-4-fluorophenyl)-3,4-dimethyl-6-methoxy-1H-pyrrolo[3,2-c]quinoline	Investigative	9840636	C21H19FN2O	334.4	CC1=C(C=CC(=C1)F)N2C=C(C3=C(N=C4C(=C32)C=CC=C4OC)C)C	IC50 = 72000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BJ9QN4	2-(5,6-Dimethoxy-1H-benzoimidazole-2-sulfinylmethyl)-phenylamine	Investigative	13754168	C16H17N3O3S	331.4	COC1=C(C=C2C(=C1)NC(=N2)S(=O)CC3=CC=CC=C3N)OC	IC50 = 120000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BK50XS	2-[2-(4-Methoxy-3,5-dimethyl-pyridin-2-yl)-ethyl]-2-methyl-2,3-dihydro-benzothiazole	Investigative	44299282	C18H22N2OS	314.4	CC1=CN=C(C(=C1OC)C)CCC2(NC3=CC=CC=C3S2)C	IC50 = 98000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BP65DY	1-(2-Methyl-4-fluorophenyl)-6-methoxy-1H-pyrrolo[3,2-c]quinoline-3-ethanol	Investigative	44327861	C21H19FN2O2	350.4	CC1=C(C=CC(=C1)F)N2C=C(C3=CN=C4C(=C32)C=CC=C4OC)CCO	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BQC89H	4-Amino-3-(1H-benzoimidazole-2-sulfinylmethyl)-benzoic acid ethyl ester	Investigative	14064693	C17H17N3O3S	343.4	CCOC(=O)C1=CC(=C(C=C1)N)CS(=O)C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BV67XD	2-[[2-[Amino]-3-(methoxycarbonyl)benzyl]sulfinyl]-1H-benzimidazole	Investigative	14064694	C16H15N3O3S	329.4	COC(=O)C1=CC=CC(=C1N)CS(=O)C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BX4ZO0	3-Methyl-1-o-tolyl-6-trifluoromethoxy-1H-pyrrolo[3,2-c]quinoline	Investigative	9798780	C20H15F3N2O	356.3	CC1=CC=CC=C1N2C=C(C3=CN=C4C(=C32)C=CC=C4OC(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BXF9U7	2-[2-(2-Hydroxy-ethoxy)-4-methoxy-phenylmethanesulfinyl]-N-pyridin-4-yl-nicotinamide	Investigative	10788603	C21H21N3O5S	427.5	COC1=CC(=C(C=C1)CS(=O)C2=C(C=CC=N2)C(=O)NC3=CC=NC=C3)OCCO	IC50 = 59000 nM	Poor binder
T92687	Gastric H(+)/K(+) ATPase	BYJ25T	[2-Acetyloxy-4-[2-[(N'-benzylcarbamimidoyl)amino]-1,3-thiazol-4-yl]phenyl] acetate;hydrochloride	Investigative	49860949	C21H21ClN4O4S	460.9	CC(=O)OC1=C(C=C(C=C1)C2=CSC(=N2)NC(=NCC3=CC=CC=C3)N)OC(=O)C.Cl	IC50 ~ 50000 nM	Poor binder